WB | 咨询技术 | Human,Mouse,Rat |
IF | 1/20-1/50 | Human,Mouse,Rat |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 | Human,Mouse,Rat |
ICC | 1/50-1/200 | Human,Mouse,Rat |
FCM | 1/20-1/100 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | DDX48; EIF4A3; eIF4AIII; hNMP 265; NMP 265; NMP265; NUK34;;eIF4A3 |
WB Predicted band size | 47 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human eIF4A3 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是3条关于eIF4A3抗体的参考文献(示例为虚构内容,实际文献需根据真实数据库检索):
1. **文献名称**: *"eIF4A3 is a critical component of the exon junction complex involved in nonsense-mediated mRNA decay"*
**作者**: Lejeune F., et al.
**摘要**: 本研究利用特异性eIF4A3抗体,通过免疫共沉淀和质谱分析,证实eIF4A3与外显子连接复合体(EJC)核心蛋白相互作用,并揭示其在无义介导的mRNA降解(NMD)中的调控作用。
2. **文献名称**: *"Antibody-based profiling of eIF4A3 expression in human cancers reveals its association with tumor progression"*
**作者**: Wang Y., et al.
**摘要**: 通过开发高特异性eIF4A3单克隆抗体,研究者分析了多种癌症组织中eIF4A3的蛋白表达水平,发现其过表达与肿瘤转移和不良预后显著相关,提示其作为潜在生物标志物的价值。
3. **文献名称**: *"Functional characterization of eIF4A3 in RNA splicing using CRISPR/Cas9 and antibody-mediated depletion"*
**作者**: Silva R., et al.
**摘要**: 结合CRISPR/Cas9基因编辑技术和eIF4A3抗体介导的蛋白敲降实验,证明eIF4A3在前体mRNA剪接中的必要性,并通过RNA-seq数据揭示其靶向调控的剪接事件。
如需真实文献,建议在PubMed或Web of Science检索关键词“eIF4A3 antibody”或“eIF4A3 function”,并筛选涉及抗体应用的论文。
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