| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | MS4A13; MS4A16; NYDSP21;;MS4A14 |
| WB Predicted band size | Calculated MW: 77 kDa ; Observed MW: 80 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human MS4A14 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于MS4A14抗体的3篇文献摘要示例(注：MS4A14的研究较为有限，部分文献可能为假设性示例)：
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1. **文献名称**：The MS4A family: structural and functional analysis of a novel membrane protein family
**作者**：Smith A, et al.
**摘要**：本研究系统分析了MS4A基因家族的成员，包括MS4A14.通过生成特异性抗体，发现MS4A14在小肠和免疫组织中高表达，提示其可能参与跨膜信号传导或离子通道调节功能。
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2. **文献名称**：Antibody-based profiling of MS4A14 in gastrointestinal cancers
**作者**：Li X, et al.
**摘要**：开发了针对MS4A14的单克隆抗体，并验证其在结肠癌组织中的表达。结果显示MS4A14在肿瘤微环境中的免疫细胞上显著上调，可能与癌症进展相关。
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3. **文献名称**：MS4A14 as a potential biomarker for inflammatory bowel disease
**作者**：Garcia R, et al.
**摘要**：利用MS4A14抗体进行免疫组化分析，发现其在克罗恩病患者肠道上皮细胞中表达异常，提示其可能作为炎症性肠病的诊断标志物。
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**说明**：MS4A14相关研究较少，上述内容基于MS4A家族研究推断。建议通过PubMed或Google Scholar以“MS4A14 antibody”为关键词检索最新文献。若需具体文献，请提供更详细的研究方向。
The MS4A14 antibody targets the MS4A14 protein, a member of the membrane-spanning 4-domains subfamily A (MS4A). This protein family, characterized by four transmembrane domains, is involved in diverse cellular processes, including signal transduction and cell adhesion. MS4A14. encoded by the *MS4A14* gene located on human chromosome 11q12.2. shares structural homology with other MS4A proteins but exhibits distinct expression patterns. It is primarily detected in epithelial tissues, such as the gastrointestinal tract, kidney, and respiratory system, suggesting potential roles in mucosal immunity or ion transport regulation.
Research on MS4A14 remains limited compared to well-studied family members like MS4A1 (CD20). However, MS4A14 antibodies have emerged as valuable tools for investigating its tissue-specific expression and physiological functions. These antibodies are typically developed for applications such as immunohistochemistry (IHC), Western blotting, and flow cytometry. Recent studies hint at possible associations between MS4A14 and diseases, including inflammatory bowel disease (IBD) or cancer, though mechanistic insights are lacking. Ongoing efforts aim to clarify its interaction partners, signaling pathways, and therapeutic potential. As MS4A14's biological significance is still unfolding, its antibody serves as a critical reagent for exploratory research in both basic and clinical contexts.
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