| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | MIP224; PSMC4; RPT3; Tat binding protein 7; TBP 7;;PSMC4 |
| WB Predicted band size | 47 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human PSMC4 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
+ +
以下是关于TBP7抗体的假设性参考文献示例(注：TBP7并非广泛研究的蛋白，以下内容为模拟示例，建议核实具体蛋白名称或补充关键词)：
---
1. **文献名称**: *"Development of a Monoclonal Antibody Against TBP7 for Studying Transcriptional Dysregulation in Cancer"*
**作者**: Zhang, L. et al.
**摘要**: 本研究开发了一种高特异性抗人TBP7的单克隆抗体，用于检测TBP7在多种癌细胞系中的异常表达。抗体经WB和IHC验证，证实TBP7在肿瘤组织中高表达，可能与转录失调相关。
2. **文献名称**: *"TBP7 Antibody Characterization in Plant Proteomic Studies"*
**作者**: Müller, S. et al.
**摘要**: 报道了一种多克隆抗体的制备，用于检测植物中TBP7同源蛋白。通过免疫沉淀和质谱分析，揭示了TBP7在拟南芥胁迫响应中的潜在作用。
3. **文献名称**: *"Comparative Analysis of Commercial TBP7 Antibodies for Specificity Validation"*
**作者**: Johnson, R. & Patel, K.
**摘要**: 系统评估了市售TBP7抗体的交叉反应性，发现部分抗体存在非特异性结合。研究强调了抗体验证的重要性，并推荐了适用于ChIP-seq的可靠试剂。
---
**注意**：若实际检索困难，建议确认蛋白名称准确性(如是否涉及拼写变异，例：TBP-7、TAP7或TAF7)，或结合具体研究领域(如转录调控、疾病标记物)扩展检索。真实文献可通过PubMed、Google Scholar以关键词“TBP7 antibody”或“anti-TBP7”查询。
The Tbp7 antibody targets TATA-box-binding protein 7 (TBP7), a conserved component of the transcription factor IID (TFIID) complex critical for RNA polymerase II-mediated gene transcription. TBP7. part of the TBP family, binds to TATA-box promoter elements to initiate assembly of the pre-initiation complex, enabling precise regulation of gene expression. It is involved in diverse cellular processes, including cell cycle control, differentiation, and stress responses. Dysregulation of TBP7 has been implicated in cancers and neurodegenerative diseases, underscoring its role in maintaining genomic stability and cellular function.
Developed in hosts like rabbits or mice, the Tbp7 antibody is commonly used in Western blotting, immunofluorescence, and chromatin immunoprecipitation (ChIP) to analyze protein expression, subcellular localization, and promoter-binding activity. Its specificity is validated against recombinant or endogenous TBP7 in human, mouse, and rat models, ensuring minimal cross-reactivity with related TBP-family proteins. Researchers utilize this tool to explore transcriptional mechanisms, disease-associated TBP7 alterations, and therapeutic targeting. Applications span oncology, where aberrant TBP7 activity may drive tumorigenesis, and developmental studies examining its role in tissue-specific gene regulation. Rigorous validation ensures reliability, making the Tbp7 antibody a key reagent for dissecting transcriptional networks and their pathological disruptions.
×
