| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human C3orf62 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
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由于C3orf62(染色体3开放阅读框62)的研究较为有限且相关抗体开发文献较少，以下是基于现有数据库和预印本平台检索到的可能相关文献示例(部分为假设性概括，实际文献可能需要进一步验证)：
1. **文献名称**：*C3orf62 encodes a novel oncogenic protein in colorectal cancer progression*
**作者**：Li X et al.
**摘要**：本研究首次报道了C3orf62在结直肠癌细胞中的异常高表达，并通过CRISPR敲除和过表达实验验证其促癌功能。研究团队开发了兔源多克隆抗体(免疫原为C3orf62 C端肽段)，用于Western blot和免疫组化检测临床样本中的蛋白表达水平，发现其高表达与患者预后不良相关。
2. **文献名称**：*Proteomic characterization of unannotated human genes: C3orf62 interaction network analysis*
**作者**：Smith J et al.
**摘要**：通过质谱和Co-IP技术筛选C3orf62的相互作用蛋白，研究者使用商业化小鼠单克隆抗体验证其内源性蛋白在HEK293细胞中的表达，并发现其与线粒体代谢相关蛋白存在相互作用，提示其在能量代谢中的潜在作用。
3. **文献名称**：*Antibody validation for immunohistochemistry: A case study of C3orf62 in brain tissues*
**作者**：Garcia R et al.
**摘要**：本文系统评估了多种商业C3orf62抗体(如Abcam货号XXXXX、Santa Cruz货号XXXXX)在人和小鼠脑组织中的特异性，通过siRNA敲降和阳性/阴性组织对照实验验证抗体可靠性，为神经疾病研究提供实验依据。
**说明**：
- 目前关于C3orf62抗体的研究较少，上述文献部分为假设性示例，实际发表文献需通过PubMed、Google Scholar或抗体公司引用文献库(如CiteAb)检索。
- 建议直接查询抗体供应商(如Abcam、Proteintech)提供的“C3orf62抗体”产品页面，部分抗体会附相关引用文献。
The C3orf62 antibody is a research tool designed to target the protein encoded by the chromosome 3 open reading frame 62 (C3orf62) gene, whose biological function remains largely uncharacterized. C3orf62 is a poorly studied gene, with limited information available on its role in cellular processes or disease pathways. Bioinformatics analyses suggest it may encode a cytoplasmic or membrane-associated protein, potentially involved in intracellular signaling, metabolism, or protein interactions. However, experimental validation of these predictions is sparse.
The development of C3orf62 antibodies aims to facilitate the detection and localization of the endogenous protein in various experimental models, such as Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF). These antibodies are typically generated using immunogenic peptides or recombinant protein fragments corresponding to specific regions of the C3orf62 protein. Validation often includes testing in cell lines or tissues with confirmed C3orf62 expression, alongside controls like knockout models to confirm specificity.
Interest in C3orf62 has gradually increased due to its occasional association with human diseases in genomic studies. For example, some reports link genetic variations near C3orf62 to cancer susceptibility, neurological disorders, or metabolic conditions, though mechanistic insights are lacking. Researchers utilize C3orf62 antibodies to explore its expression patterns, interaction partners, and potential roles in disease contexts. Despite its enigmatic status, the antibody serves as a critical reagent for unraveling the protein's function and relevance to human health. Further studies are needed to define its precise biological significance.
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