Mouse Monoclonal AARSD1 Antibody

The AARSD1 (Alanyl-tRNA Synthetase Domain-Containing Protein 1) antibody is a tool used to study the role of AARSD1. a protein encoded by the AARSD1 gene. AARSD1 belongs to the aminoacyl-tRNA synthetase family, which plays a critical role in protein synthesis by attaching specific amino acids to their corresponding tRNAs. While its exact biological function remains under investigation, AARSD1 is proposed to interact with alanyl-tRNA synthetase (AARS), potentially modulating its activity or participating in non-canonical pathways beyond translation. Research suggests AARSD1 may influence mitochondrial function, cellular stress responses, and possibly neurodegenerative or metabolic disorders. Antibodies against AARSD1 are utilized in techniques like Western blotting, immunofluorescence, and immunohistochemistry to detect protein expression, localization, and interactions in various tissues or disease models. These studies aim to clarify AARSD1's involvement in health and disease, including its potential links to cancer, neurodegeneration, or rare genetic conditions. However, the protein's low abundance and overlapping domains with other synthetases pose challenges, requiring antibody-specific validation. Ongoing research seeks to unravel its molecular mechanisms and therapeutic relevance.