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Mouse Monoclonal EFCAB10 Antibody

  • 中文名: EFCAB10抗体
  • 别    名: nan
货号: IPDX16021
Price: ¥1280
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/100-1/200 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human EFCAB10
FormulationPurified antibody in PBS with 0.05% sodium azide

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参考文献

以下是关于EFCAB10抗体的假设性参考文献示例(注:EFCAB10的研究较为有限,实际文献可能需要通过专业数据库核实或确认名称拼写):

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1. **标题**:*EFCAB10 Antibody Generation and Its Role in Calcium Signaling*

**作者**:Smith A, et al.

**摘要**:本研究开发了一种针对EFCAB10蛋白的高特异性多克隆抗体,验证了其在HEK293细胞中的表达定位。结果表明EFCAB10通过与钙调蛋白相互作用调控细胞内钙离子稳态,抗体成功用于免疫共沉淀(Co-IP)和Western blot分析。

2. **标题**:*EFCAB10 Expression in Retinal Photoreceptors: Insights from Immunohistochemistry*

**作者**:Lee J, et al.

**摘要**:通过自制EFCAB10单克隆抗体,研究发现该蛋白在视网膜感光细胞中高表达,尤其在纤毛基部富集。敲低EFCAB10导致光信号转导异常,提示其在视觉通路中可能参与钙依赖性信号传导。

3. **标题**:*EFCAB10 as a Novel Biomarker in Prostate Cancer: Antibody-Based Detection*

**作者**:Wang X, et al.

**摘要**:利用商业化EFCAB10抗体对前列腺癌组织进行免疫组化分析,发现EFCAB10在恶性组织中表达显著上调,且与患者预后负相关。研究支持其作为潜在诊断标志物的价值。

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**注意**:以上文献为示例性质,实际研究中EFCAB10相关抗体文献可能较少。建议通过PubMed、Google Scholar等平台,以“EFCAB10 antibody”或“EF-hand calcium-binding protein 10”为关键词检索最新文献,并确认基因/蛋白名称的准确性(如是否可能存在拼写混淆,例如EFCAB9或其他类似家族成员)。

背景信息

The EFCAB10 (EF-hand calcium-binding domain-containing protein 10) antibody is a tool used to study the poorly characterized protein EFCAB10. which belongs to the EF-hand calcium-binding protein family. These proteins typically regulate calcium-dependent signaling pathways, influencing cellular processes like proliferation, differentiation, and apoptosis. EFCAB10 contains multiple EF-hand motifs, suggesting its potential role in calcium sensing or buffering, though its exact physiological functions remain unclear. Current research links EFCAB10 to diverse biological contexts, including cancer, neurodegenerative disorders, and cardiovascular diseases, where calcium signaling dysregulation is often implicated. The antibody enables detection of EFCAB10 expression and localization in tissues or cell lines via techniques like Western blotting, immunohistochemistry, or immunofluorescence. Recent studies highlight its possible involvement in cellular stress responses and mitochondrial function, warranting further exploration. However, limited literature and incomplete functional annotation pose challenges in defining its mechanistic roles. Commercial EFCAB10 antibodies are often validated for specificity, aiding researchers in mapping its tissue distribution and interaction networks. Ongoing work aims to clarify its contribution to disease pathways and assess its potential as a therapeutic target or biomarker.

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