| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human SAMD13 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
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以下是关于SAMD13抗体的示例参考文献(注：部分内容为虚构示例，实际文献需通过学术数据库核实)：
1. **文献名称**: "Characterization of a Novel Anti-SAMD13 Antibody for Immunohistochemical Applications"
**作者**: Lee, J. et al.
**摘要**: 本研究开发并验证了一种高特异性SAMD13多克隆抗体，可用于人组织样本的免疫组化分析。抗体通过Western blot和免疫荧光验证，证实其在检测SAMD13蛋白表达中的可靠性，并应用于乳腺癌组织中SAMD13表达水平与预后的相关性分析。
2. **文献名称**: "SAMD13 Regulates Neuronal Development and Its Antibody-Based Detection in Mouse Brain"
**作者**: Smith, R. & Gonzalez, A.
**摘要**: 文章探讨了SAMD13在小鼠脑发育中的功能，利用商业化SAMD13抗体(货号ABX-2030)进行免疫印迹和免疫染色，发现SAMD13在海马体神经元分化中高表达，提示其可能参与神经突触形成。
3. **文献名称**: "SAMD13 as a Potential Biomarker in Colorectal Cancer: Validation of a Monoclonal Antibody"
**作者**: Wang, Y. et al.
**摘要**: 研究团队通过杂交瘤技术制备了抗SAMD13单克隆抗体，验证其在结直肠癌组织中的特异性。结果显示SAMD13低表达与肿瘤转移相关，提示其可能作为预后标志物。
4. **文献名称**: "Cross-Species Reactivity of Anti-SAMD13 Antibodies and Functional Implications"
**作者**: Patel, S. et al.
**摘要**: 评估了多种SAMD13抗体在小鼠、斑马鱼和人类细胞中的交叉反应性，发现部分抗体具有种属特异性。研究还揭示了SAMD13在细胞周期调控中的作用，为后续功能研究提供工具支持。
**建议**：以上为示例文献，实际研究中请通过PubMed、Web of Science等平台以“SAMD13 antibody”或“SAMD13 protein”为关键词检索最新研究，并优先选择近3-5年、高被引或权威期刊的论文。
The SAMD13 (Sterile Alpha Motif Domain-containing 13) antibody is a tool used to detect and study the SAMD13 protein, a member of the SAM domain-containing protein family. SAM domains are evolutionarily conserved protein modules involved in protein-protein interactions, often regulating diverse cellular processes such as signal transduction, transcriptional regulation, and apoptosis. SAMD13. though less characterized compared to other SAM domain proteins, is implicated in immune responses and cancer biology. Studies suggest its potential role in modulating inflammatory pathways and tumor progression, with altered expression observed in certain cancers, including hepatocellular carcinoma and glioblastoma.
The SAMD13 antibody is typically developed using immunogens derived from specific epitopes of the human SAMD13 protein. It enables researchers to investigate SAMD13's expression patterns, subcellular localization, and interactions via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Its applications extend to both basic research and clinical studies, particularly in understanding SAMD13's functional mechanisms in disease contexts. However, comprehensive biological roles of SAMD13 remain under exploration, necessitating further validation of antibody specificity and functional studies. Commercial SAMD13 antibodies are available from various suppliers, often accompanied by validation data in common cell lines or tissues. Researchers should optimize experimental conditions to ensure reproducibility across different models.
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