| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human PPP1R27 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
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以下是关于PPP1R27抗体的3篇示例文献(注：以下内容为虚构示例，实际文献需通过学术数据库检索确认)：
1. **文献名称**：*"Characterization of PPP1R27 in skeletal muscle differentiation using a novel polyclonal antibody"*
**作者**：Smith J et al.
**摘要**：本研究开发了一种针对PPP1R27羧基末端的兔源多克隆抗体，验证了其在人骨骼肌细胞分化过程中通过调控PP1磷酸酶活性影响肌管形成的功能。
2. **文献名称**：*"PPP1R27 regulates neuronal synaptic plasticity via PP1-dependent mechanisms: Evidence from knockout mice and antibody-based localization"*
**作者**：Chen L et al.
**摘要**：通过免疫荧光和Western blot分析，作者利用自制的PPP1R27单克隆抗体证实其在海马神经元突触后膜的富集，并发现其缺失导致小鼠学习能力受损。
3. **文献名称**：*"A role of PPP1R27 in hepatic insulin signaling revealed by targeted antibody disruption"*
**作者**：Yamamoto K et al.
**摘要**：该研究通过靶向PPP1R27的小鼠单克隆抗体阻断实验，证明其通过与PP1相互作用调控肝脏胰岛素受体信号通路，影响糖代谢稳态。
**提示**：实际研究中PPP1R27相关抗体文献可能较少，建议通过PubMed或Google Scholar以“PPP1R27 antibody”或“PPP1R27 + [研究领域]”为关键词检索最新结果，并优先选择经抗体验证(如KO验证、应用实例)的论文。
The PPP1R27 (Protein Phosphatase 1 Regulatory Subunit 27) antibody is a tool used to study the role of PPP1R27. a regulatory protein that interacts with Protein Phosphatase 1 (PP1). PP1 is a serine/threonine phosphatase involved in diverse cellular processes, including signal transduction, metabolism, and cell cycle regulation. PPP1R27 acts as a regulatory subunit, guiding PP1 to specific substrates or cellular compartments to modulate its activity. While the exact biological functions of PPP1R27 remain under investigation, studies suggest its involvement in cellular differentiation, stress responses, and metabolic pathways, particularly in skeletal muscle and neuronal tissues.
Antibodies targeting PPP1R27 enable researchers to detect its expression, localization, and interactions in various experimental models, such as Western blotting, immunohistochemistry, and immunofluorescence. These antibodies are critical for exploring PPP1R27's regulatory mechanisms and its potential implications in diseases like metabolic disorders, neurodegeneration, or cancer. However, research on PPP1R27 is still emerging, with limited data on its full physiological range or disease-related mutations. Commercial availability of these antibodies supports ongoing efforts to unravel PPP1R27's role in PP1-mediated signaling networks and its broader impact on cellular homeostasis.
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