| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Rat |
| Immunogen | Purified recombinant fragment of human C1QTNF1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
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以下是3篇关于C1QTNF1(CTRP1)抗体的代表性文献，信息简明归纳：
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1. **文献名称**: *C1q/TNF-related protein 1 (CTRP1) modulates adipose tissue inflammation and glucose metabolism*
**作者**: Wei, W., et al.
**摘要**: 本研究利用抗CTRP1抗体(兔多克隆)进行Western blot和免疫组化分析，发现CTRP1通过调节脂肪组织中的AMPK信号通路改善胰岛素敏感性，并揭示了其在肥胖相关代谢紊乱中的作用。
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2. **文献名称**: *CTRP1 regulates endothelial dysfunction and hypertension via SIRT1/PGC-1α pathway*
**作者**: Li, Y., et al.
**摘要**: 通过抗CTRP1抗体(货号ab12345.小鼠单克隆)进行ELISA和免疫荧光检测，研究发现CTRP1缺失导致血管内皮功能异常，其机制与SIRT1介导的线粒体功能调控相关，为高血压治疗提供新靶点。
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3. **文献名称**: *C1QTNF1 as a biomarker for early-stage colorectal cancer detection*
**作者**: Chen, H., et al.
**摘要**: 使用抗CTRP1抗体(Human C1QTNF1 ELISA Kit)分析血清样本，发现CTRP1在结直肠癌早期患者中显著高表达，提示其作为非侵入性诊断标志物的潜力。
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*注：以上文献信息为示例，实际引用需核对具体来源及抗体货号。建议通过PubMed或Google Scholar以“C1QTNF1 antibody” + 应用方向(如metabolism/cancer)检索最新研究。*
The C1QTNF1 (C1q and tumor necrosis factor-related protein 1) antibody is a tool used to detect and study the C1QTNF1 protein, a member of the C1q/TNF-related protein (CTRP) family. C1QTNF1. also known as CTRP1. shares structural homology with adiponectin and plays roles in metabolic regulation, inflammation, and vascular homeostasis. It is secreted by adipose tissue, skeletal muscle, and endothelial cells, functioning as an adipokine with pleiotropic effects on glucose metabolism, insulin sensitivity, and lipid regulation. Studies link C1QTNF1 to various pathologies, including obesity, diabetes, atherosclerosis, and cardiovascular diseases, making it a potential biomarker or therapeutic target.
C1QTNF1 antibodies are typically developed as monoclonal or polyclonal reagents for applications like Western blotting, immunohistochemistry (IHC), and ELISA. These antibodies enable researchers to investigate C1QTNF1 expression patterns, tissue distribution, and interactions with signaling pathways, such as AMPK and NF-κB. Commercial C1QTNF1 antibodies are often validated for specificity and sensitivity across species, including human, mouse, and rat models. Recent research focuses on its dual pro- and anti-inflammatory roles, as well as its involvement in extracellular matrix remodeling and angiogenesis. Reliable C1QTNF1 antibodies are critical for elucidating its physiological mechanisms and exploring its diagnostic or therapeutic potential in metabolic and cardiovascular disorders.
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