| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human IFNW1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
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以下是关于IFNW1抗体的虚构参考文献示例(请注意，这些文献为示例用途，实际研究请通过学术数据库查询)：
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1. **文献名称**: *Development and Characterization of a Monoclonal Antibody Specific for Human Interferon Omega-1 (IFNW1)*
**作者**: Smith J, et al.
**摘要**: 本研究报道了一种针对人IFNW1的高特异性单克隆抗体的开发，通过杂交瘤技术筛选并验证其结合活性。该抗体在ELISA和Western blot中表现出高灵敏度，可用于IFNW1蛋白的定量检测及功能研究。
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2. **文献名称**: *IFNW1 Antibody Neutralizes Viral Replication in vitro*
**作者**: Lee H, et al.
**摘要**: 文章验证了IFNW1抗体在体外抗病毒模型中的作用，证明其能有效中和IFNW1的生物活性，抑制病毒在宿主细胞内的复制，为抗病毒治疗提供了潜在工具。
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3. **文献名称**: *Expression Profiling of IFNW1 and Its Therapeutic Antibody in Autoimmune Disorders*
**作者**: Garcia R, et al.
**摘要**: 研究分析了IFNW1在自身免疫疾病模型中的表达变化，并测试了一种治疗性抗体对炎症因子的调控作用，提示IFNW1抗体可能具有免疫调节潜力。
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4. **文献名称**: *Structural Insights into IFNW1-Antibody Interactions by Cryo-EM*
**作者**: Chen L, et al.
**摘要**: 通过冷冻电镜技术解析了IFNW1与其抗体复合物的三维结构，揭示了抗体结合表位及作用机制，为优化抗体药物设计提供了结构基础。
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如需真实文献，建议在 **PubMed** 或 **Web of Science** 中检索关键词：`IFNW1 antibody`、`Interferon Omega-1`。
The IFNW1 antibody is a research tool designed to detect interferon omega-1 (IFNW1), a member of the type I interferon (IFN) family. Type I IFNs, including IFN-α, IFN-β, and IFN-ω, are cytokines critical for innate immunity, antiviral responses, and immune regulation. IFNW1 shares structural and functional similarities with other type I IFNs, signaling through the IFN-α/β receptor (IFNAR) to activate JAK-STAT pathways, which induce interferon-stimulated genes (ISGs) to combat viral infections and modulate immune cell activity. While less studied than IFN-α/β, IFNW1 is expressed in immune cells and certain tissues, with potential roles in autoimmune diseases, viral defense, and cancer immunotherapy.
IFNW1 antibodies are typically monoclonal or polyclonal, generated in hosts like rabbits or mice, and validated for applications such as Western blotting, ELISA, immunohistochemistry, or flow cytometry. They enable researchers to study IFNW1 expression, localization, and interaction with signaling molecules in cellular or disease models. Commercial IFNW1 antibodies often include specificity validation via knockout controls or neutralizing assays. Research involving IFNW1 is relevant in understanding antiviral mechanisms, immune dysregulation (e.g., lupus or psoriasis), and therapeutic strategies leveraging IFN pathways. However, its distinct biological functions and clinical implications compared to other type I IFNs remain an active area of investigation.
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