Mouse Monoclonal KIFBP Antibody

The KIFBP (Kinesin Family Binding Protein) antibody is a crucial tool in studying the role of KIFBP, a protein implicated in regulating kinesin motor proteins involved in intracellular transport. Kinesins are microtubule-dependent motors that facilitate the movement of organelles, vesicles, and macromolecules within cells. KIFBP interacts with specific kinesin family members, modulating their activity, stability, or localization, thereby influencing processes like mitotic spindle formation, axonal transport, and cell division. Dysregulation of KIFBP has been linked to pathologies, including neurodegenerative disorders and cancers, where altered intracellular transport contributes to disease progression. Researchers employ KIFBP antibodies in techniques such as Western blotting, immunofluorescence, and immunohistochemistry to detect protein expression levels, subcellular distribution, and interactions in cellular or tissue samples. These studies help elucidate KIFBP's mechanistic contributions to both normal physiology and disease states. Recent work also explores its potential as a therapeutic target or biomarker. The antibody's specificity and sensitivity are critical for ensuring accurate experimental results, driving advances in understanding kinesin-related cellular dynamics and associated disorders.