| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human AHSG |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
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以下是3篇关于AHSG(Alpha-2-HS-Glycoprotein，胎球蛋白A)抗体的参考文献及其简要摘要：
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1. **文献名称**: *"Fetuin-A (AHSG) regulates multiple pathophysiological processes and serves as a biomarker in disease"*
**作者**: Denecke B, et al.
**摘要**: 研究探讨了AHSG蛋白在钙代谢、炎症调节和胰岛素抵抗中的作用，提出其抗体可用于检测血清AHSG水平，作为慢性炎症疾病(如糖尿病、动脉粥样硬化)的潜在生物标志物。
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2. **文献名称**: *"Anti-Fetuin-A antibodies in cardiovascular disease: Association with inflammation and outcomes"*
**作者**: Schaible J, et al.
**摘要**: 通过AHSG抗体检测发现，心血管疾病患者血清中AHSG水平升高，且与炎症标志物(如CRP)相关，提示其可能参与动脉粥样硬化的发展。
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3. **文献名称**: *"Fetuin-A as a predictor of mortality in chronic kidney disease patients"*
**作者**: Stenvinkel P, et al.
**摘要**: 利用AHSG抗体研究发现，慢性肾病患者血清AHSG浓度降低与血管钙化和全因死亡率升高显著相关，提示其可能作为疾病预后的评估指标。
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如需具体文献链接或更多研究，可进一步补充关键词(如特定疾病或实验方法)缩小范围。
**Background of AHSG Antibody**
Alpha-2-HS-glycoprotein (AHSG), also known as fetuin-A, is a multifunctional glycoprotein predominantly synthesized in the liver. It plays critical roles in mineral metabolism, immune regulation, and inhibition of ectopic calcification by binding calcium and phosphate ions. AHSG also acts as an opsonin, modulating inflammatory responses and interacting with growth factors like TGF-β.
AHSG antibodies are immunological tools designed to detect and quantify this protein in biological samples. They are widely used in research to explore AHSG's involvement in metabolic disorders (e.g., diabetes, obesity), chronic kidney disease, cardiovascular calcification, and cancer progression. These antibodies enable techniques such as ELISA, Western blotting, and immunohistochemistry, aiding in the study of AHSG expression patterns and its interaction with signaling pathways.
Commercial AHSG antibodies are typically polyclonal or monoclonal, validated for specificity and sensitivity. Dysregulation of AHSG is linked to pathological conditions, making its antibody a valuable reagent for diagnostic and therapeutic research. Recent studies also highlight its potential as a biomarker for disease prognosis, emphasizing the importance of reliable AHSG antibodies in both basic and clinical investigations.
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