| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human MAST4 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
+ +
以下是关于MAST4抗体的3篇模拟参考文献示例，供参考：
---
1. **文献名称**：*MAST4 kinase regulates neuronal development via phosphorylation of microtubule-associated proteins*
**作者**：Chen L, et al.
**摘要**：本研究利用特异性MAST4抗体，通过免疫组织化学和Western blot分析，揭示了MAST4在小鼠大脑皮层神经元发育中的关键作用。结果显示，MAST4通过磷酸化微管相关蛋白调控轴突导向和树突分支。
---
2. **文献名称**：*Characterization of a novel monoclonal antibody against MAST4 for cancer biomarker studies*
**作者**：Rodriguez S, et al.
**摘要**：该研究开发了一种高特异性抗MAST4单克隆抗体，并验证了其在免疫荧光和流式细胞术中的应用。结果显示，MAST4在胶质母细胞瘤中高表达，可能作为潜在治疗靶点。
---
3. **文献名称**：*MAST4 interacts with the Hippo pathway effector YAP1 in hepatocellular carcinoma*
**作者**：Wang Y, et al.
**摘要**：通过免疫共沉淀(Co-IP)和免疫印迹技术(使用MAST4抗体)，本研究发现MAST4与YAP1蛋白在肝癌细胞中存在直接相互作用，提示其在Hippo信号通路调控中的新机制。
---
**备注**：以上文献为示例，实际引用时需通过PubMed、Google Scholar等平台检索真实文献并核对信息。建议使用关键词“MAST4 antibody”、“MAST4 kinase”或“MAST4 function”进行扩展搜索。
**Background of MAST4 Antibody**
MAST4 (Microtubule-Associated Serine/Threonine Kinase 4) is a member of the MAST kinase family, which plays roles in cellular processes such as neuronal development, synaptic plasticity, and signal transduction. The MAST4 protein contains a kinase domain, a PDZ domain, and a conserved region of unknown function, enabling interactions with cytoskeletal components, membrane proteins, and signaling molecules. MAST4 is highly expressed in the brain, particularly in regions like the hippocampus and cortex, suggesting its importance in neurodevelopment and cognitive function.
MAST4 antibodies are immunological tools designed to detect and study the expression, localization, and function of the MAST4 protein. These antibodies are widely used in techniques like Western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF) to investigate MAST4's role in health and disease. Research has linked MAST4 dysregulation to neurological disorders, including Alzheimer’s disease, and cancers such as glioblastoma and breast cancer, where it may influence tumor progression or drug resistance.
Commercial MAST4 antibodies are typically validated for specificity and sensitivity across applications, aiding in both basic research and clinical studies. Their development has advanced understanding of MAST4’s molecular mechanisms, though its full biological significance remains under exploration.
×
