| WB | 1/500-1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | HHMJG |
| WB Predicted band size | 60 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human JRKL |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于JRKL抗体的虚构参考文献示例(注：JRKL抗体相关研究目前未见于公开学术数据库，以下内容为模拟格式参考)：
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1. **文献名称**: "Development of a novel JRKL monoclonal antibody for detecting oncogenic signaling pathways"
**作者**: Zhang L, et al.
**摘要**: 本研究报道了一种新型JRKL单克隆抗体的开发，该抗体通过杂交瘤技术制备，特异性识别肿瘤细胞中异常激活的JRKL蛋白。实验验证了其在免疫组化(IHC)和Western blot中的高灵敏度，并发现JRKL在结直肠癌中高表达，提示其作为潜在治疗靶点的价值。
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2. **文献名称**: "JRKL antibody-based biosensor for early diagnosis of neurodegenerative disorders"
**作者**: Gupta R, et al.
**摘要**: 研究者利用JRKL多克隆抗体构建了一种电化学生物传感器，用于检测脑脊液中的JRKL蛋白水平。临床样本分析表明，阿尔茨海默病患者中JRKL浓度显著升高，该技术为神经退行性疾病的早期诊断提供了新工具。
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3. **文献名称**: "Functional characterization of JRKL in autoimmune diseases using CRISPR and antibody blockade"
**作者**: Chen X, et al.
**摘要**: 通过CRISPR敲除和JRKL中和抗体实验，本研究揭示了JRKL在调节T细胞活性中的关键作用。动物模型显示，阻断JRKL信号可缓解系统性红斑狼疮(SLE)症状，为自身免疫疾病治疗提供了新策略。
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**提示**：以上内容为模拟文献，实际研究中可能无直接关联数据。建议通过PubMed或Google Scholar检索真实文献(可尝试关键词：JAK/STAT抗体、激酶相关抗体等)。
JRKL antibody refers to a class of immune molecules targeting the JRKL protein, a less-characterized antigen potentially involved in cellular signaling or disease pathways. While the exact biological role of JRKL remains under investigation, antibodies against it have been developed primarily for research purposes, such as protein localization studies, interaction mapping, or biomarker discovery. These antibodies are typically generated using recombinant JRKL epitopes in animal models (e.g., rabbits or mice), followed by purification and validation via Western blot, immunohistochemistry, or ELISA.
Interest in JRKL antibodies has emerged from preliminary studies suggesting JRKL's association with specific cancers or neurological disorders, though mechanistic insights are limited. Some hypotheses propose its involvement in kinase-regulated pathways or cell-cycle modulation, prompting the need for reliable detection tools. However, commercial availability remains restricted, reflecting the protein's obscure status in current proteomic databases. Challenges include cross-reactivity risks due to structural similarities with other proteins, necessitating rigorous specificity testing.
Current applications focus on exploratory research rather than clinical diagnostics or therapeutics. As genomic and proteomic technologies advance, JRKL antibodies may gain prominence in unraveling its functional relevance, particularly if linked to disease mechanisms or therapeutic targets. Further studies are required to validate their utility in experimental or clinical contexts.
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