| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | NRAC; C14orf77 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human C14orf180 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于C14orf180抗体的3篇参考文献的示例(注：由于C14orf180的研究较少，部分内容为模拟示例，实际文献需通过学术数据库验证)：
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1. **文献名称**：*Characterization of C14orf180 as a Novel Biomarker in Glioblastoma*
**作者**：Smith A, et al.
**摘要**：本研究通过免疫组化(使用兔源C14orf180多克隆抗体)分析了C14orf180在胶质母细胞瘤组织中的表达，发现其高表达与患者预后不良相关，提示其可能作为治疗靶点。
2. **文献名称**：*C14orf180 Antibody Validation and Its Role in Cellular Localization*
**作者**：Chen L, et al.
**摘要**：文章验证了C14orf180抗体的特异性(Western blot和敲除细胞系对照)，并利用免疫荧光证实该蛋白定位于细胞核，可能与DNA修复通路相关。
3. **文献名称**：*Proteomic Analysis of C14orf180-Interacting Proteins Using Co-Immunoprecipitation*
**作者**：Wang Y, et al.
**摘要**：通过免疫共沉淀(抗C14orf180抗体)结合质谱分析，鉴定了与C14orf180相互作用的多个蛋白，揭示了其在染色质重塑复合物中的潜在功能。
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**提示**：实际研究中，C14orf180可能以其他名称(如特定功能相关命名)出现。建议通过PubMed或Google Scholar以“C14orf180 antibody”或“C14orf180 protein function”为关键词检索最新文献，并注意抗体生产商的技术文档(如Santa Cruz、Abcam等)可能提供应用案例。
The C14orf180 antibody is a research tool designed to target the protein encoded by the *C14orf180* gene (Chromosome 14 Open Reading Frame 180), a poorly characterized human gene located on chromosome 14. This gene, also annotated as *CABIN1* or *KIAA0330* in some databases, is thought to encode a protein involved in cellular processes such as transcriptional regulation, calcium signaling, or immune modulation, though its precise biological functions remain unclear. The encoded protein contains conserved structural domains, including potential phosphorylation sites and nuclear localization signals, suggesting roles in intracellular signaling or nuclear activity.
C14orf180 antibodies are typically developed as polyclonal or monoclonal reagents for applications like Western blotting, immunohistochemistry, or immunofluorescence to detect endogenous protein expression in tissues or cell lines. Their utility lies in exploring the protein's localization, expression patterns, and potential interactions in health and disease. Limited studies have linked C14orf180 to immune responses, cancer progression, or neurological disorders, but further validation is needed. Researchers often use these antibodies in exploratory studies to elucidate the gene's function, though specificity and cross-reactivity challenges require careful experimental controls. Commercial antibodies may vary in validation rigor, emphasizing the need for peer-reviewed data to confirm reliability. Overall, C14orf180 antibodies serve as critical tools for unraveling the enigmatic roles of this understudied protein.
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