首页 / 产品 / 抗体 / 一抗

Rabbit Polyclonal AHCTF1 Antibody

  • 中文名: AHCTF1抗体
  • 别    名: ELYS; MST108; TMBS62; MSTP108
货号: IPDX13313
Price: ¥1180
数量:
大包装询价

验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/25-1/100 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

AliasesELYS; MST108; TMBS62; MSTP108
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human AHCTF1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

参考文献

以下是关于AHCTF1抗体的3篇参考文献示例(内容为虚构,仅供参考):

1. **文献名称**:*AHCTF1/ELYS regulates mitotic nuclear pore complex assembly through its interaction with Nup107*

**作者**:Gómez-Saldivar G, et al.

**摘要**:该研究利用AHCTF1特异性抗体,通过免疫荧光和蛋白质印迹技术,揭示了AHCTF1在细胞有丝分裂过程中与核孔复合体蛋白Nup107相互作用,调控核膜重组的关键机制。

2. **文献名称**:*Depletion of AHCTF1 disrupts spindle formation and chromosome segregation in cancer cells*

**作者**:Kimura N, et al.

**摘要**:通过RNA干扰和AHCTF1抗体的共聚焦显微成像,作者发现AHCTF1的缺失导致癌细胞纺锤体异常和染色体错误分离,提示其在维持基因组稳定性中的重要作用。

3. **文献名称**:*AHCTF1 as a potential biomarker in colorectal cancer progression*

**作者**:Wang L, et al.

**摘要**:研究采用AHCTF1抗体对结直肠癌组织进行免疫组化分析,发现AHCTF1表达水平与肿瘤分期和转移显著相关,表明其可作为预后评估的潜在标志物。

(注:以上文献为示例性内容,实际引用请查询真实数据库如PubMed或Web of Science。)

背景信息

The AHCTF1 antibody is a research tool designed to detect AHCTF1 (also known as ELYS or MSTP118), a critical protein involved in nuclear envelope reformation and mitotic spindle assembly during cell division. AHCTF1 plays a key role in recruiting essential components, such as the Nup107-160 complex, to chromatin during late mitosis, facilitating nuclear pore complex assembly and nucleocytoplasmic transport. It is also implicated in chromatin organization and regulation of gene expression. Dysregulation of AHCTF1 has been linked to genomic instability, developmental defects, and cancer progression. Researchers use AHCTF1 antibodies in techniques like Western blotting, immunofluorescence, and immunohistochemistry to study its localization, expression levels, and interactions in cellular processes. These studies help elucidate AHCTF1’s role in cell cycle regulation, cancer biology, and potential therapeutic targeting. The antibody’s specificity and validation across experimental models make it valuable for both basic and translational research aimed at understanding mechanisms underlying mitotic fidelity and disease pathogenesis.

客户数据及评论

折叠内容

大包装询价

×