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Rabbit Polyclonal CYB5D1 Antibody

  • 中文名: CYB5D1抗体
  • 别    名: nan
货号: IPDX13220
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/20-1/100 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

WB Predicted band size27 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human CYB5D1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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参考文献

以下是关于CYB5D1抗体的3篇参考文献示例(注:文献为虚拟构造,仅供格式参考,实际文献需通过学术数据库检索):

1. **文献名称**:*Characterization of a Novel Polyclonal Antibody Against Human CYB5D1 for Immunohistochemical Analysis*

**作者**:Zhang L, et al.

**摘要**:本研究报道了一种针对人源CYB5D1蛋白的多克隆抗体的开发与验证。通过免疫兔获得抗体,经Western blot和免疫组化验证其特异性,证实CYB5D1在肝脏和肾脏组织中高表达,并提示其可能参与细胞色素P450相关代谢途径。

2. **文献名称**:*CYB5D1 Expression in Breast Cancer: Correlation with Prognosis and Role in Tumor Progression*

**作者**:Tanaka K, et al.

**摘要**:利用CYB5D1特异性单克隆抗体,作者发现该蛋白在乳腺癌组织中表达上调,且高表达与患者不良预后相关。功能实验表明,CYB5D1通过调控细胞内氧化还原平衡促进肿瘤细胞侵袭。

3. **文献名称**:*Development of a CYB5D1 Knockout Mouse Model Using CRISPR/Cas9 and Antibody-Based Phenotypic Validation*

**作者**:Smith J, et al.

**摘要**:本研究构建了CYB5D1基因敲除小鼠,并采用定制抗体验证蛋白缺失表型。结果显示,CYB5D1缺失导致红细胞膜稳定性异常,提示其在脂质代谢中的潜在作用。

**提示**:实际文献需通过PubMed、Google Scholar等平台以“CYB5D1 antibody”或“CYB5D1 function”为关键词检索。建议结合研究领域(如癌症、代谢疾病)进一步筛选。

背景信息

The CYB5D1 antibody is a research tool designed to detect and study cytochrome b5 domain-containing protein 1 (CYB5D1), a member of the cytochrome b5 family. This protein is characterized by a conserved cytochrome b5-like heme-binding domain, though its precise physiological role remains less understood compared to other family members like CYB5A or CYB5R. CYB5D1 is hypothesized to participate in redox reactions, lipid metabolism, or cellular detoxification processes, potentially interacting with cytochrome P450 enzymes. Its expression has been observed in various tissues, including the liver, brain, and reproductive organs, suggesting tissue-specific functions.

CYB5D1 antibodies are typically developed in hosts such as rabbits or mice, using immunogens derived from specific CYB5D1 peptide sequences or recombinant proteins. These antibodies enable researchers to investigate CYB5D1's expression patterns, subcellular localization (e.g., endoplasmic reticulum or mitochondrial associations), and interactions via techniques like Western blotting, immunohistochemistry, or immunofluorescence. Studies using CYB5D1 antibodies may explore its role in diseases linked to metabolic dysregulation, cancer, or neurodegenerative disorders. However, limited literature and the lack of comprehensive functional studies highlight the need for further validation of CYB5D1's biological significance and the antibody's specificity. Commercial availability varies, with some suppliers offering monoclonal or polyclonal options for experimental use.

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