Rabbit Polyclonal ZC2HC1A Antibody

The ZC2HC1A antibody is designed to target the ZC2HC1A protein, a zinc finger-containing protein implicated in various cellular processes, including transcriptional regulation and cell cycle control. ZC2HC1A, also known as CXXC2 or HXC26. contains a C3HC4-type zinc finger motif at its C-terminus, which is critical for its interaction with nucleic acids or proteins. Studies suggest its involvement in ubiquitination pathways, potentially modulating protein degradation or signaling cascades. The antibody is commonly developed in rabbit or mouse hosts, using immunogens derived from specific epitopes within the ZC2HC1A sequence. It has been utilized in techniques like Western blotting, immunoprecipitation, and immunofluorescence to study ZC2HC1A's expression, localization, and interactions. Research highlights its role in diseases; for example, ZC2HC1A dysregulation is linked to cancers, where it may act as an oncogene or tumor suppressor depending on context. Additionally, its interaction with components of the ubiquitin-proteasome system underscores its importance in maintaining cellular homeostasis. Commercial antibodies often undergo validation in knockout cell lines to confirm specificity. Ongoing studies aim to clarify its precise molecular mechanisms and therapeutic potential, making ZC2HC1A a protein of growing interest in molecular biology and translational research.