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产品描述：人癌胚抗原相关细胞粘附分子6(CEACAM6)酶联免疫试剂盒为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的CEACAM6含量。CEACAM6为肿瘤相关靶点，其在多种恶性肿瘤中异常高表达，参与肿瘤细胞的增殖、迁移、侵袭等过程。研究机制多聚焦于其信号通路，其可通过与配体结合激活下游信号，促进肿瘤进展，有望成治疗癌症的新靶点。试剂盒检测范围为0.83 ng/mL-20 ng/mL，支持科研人员开展肿瘤发生机制、生物标志物筛选及抗癌药物疗效评估等研究，适用于体外定量检测细胞培养上清、临床前动物模型样本及病理组织中的CEACAM6表达水平分析，为癌症相关基础研究与转化医学提供可靠工具。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：Carcinoembryonic antigen related cell adhesion molecule 6 ELISA Kit; Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen) ELISA Kit; Carcinoembryonic antigen-related cell adhesion molecule 6 ELISA Kit; CD 66c ELISA Kit; CD66c ELISA Kit; CD66c antigen ELISA Kit; CEA LIKE PROTEIN ELISA Kit; CEACAM 6 ELISA Kit; CEACAM6 ELISA Kit; CEAL ELISA Kit; CEAM6_HUMAN ELISA Kit; MGC93832 ELISA Kit; NCA ELISA Kit; Non specific cross reacting antigen ELISA Kit; Non-specific crossreacting antigen ELISA Kit; Normal cross reacting antigen ELISA Kit; Normal cross-reacting antigen ELISA Kit
缩写：CEACAM6
Uniprot No.：P40199
种属：Homo sapiens (Human)
样本类型：serum, plasma, tissue homogenates
检测范围：0.83 ng/mL-20 ng/mL
灵敏度：0.33 ng/mL
反应时间：1-5h
样本体积：50-100ul
检测波长：450 nm
研究领域：Tags & Cell Markers
测定原理：quantitative
测定方法：Sandwich
精密度：
| Intra-assay Precision (Precision within an assay): CV%<10% | ||||||
| Three samples of known concentration were tested twenty times on one plate to assess. | ||||||
| Inter-assay Precision (Precision between assays): CV%<15% | ||||||
| Three samples of known concentration were tested in twenty assays to assess. | ||||||
线性度：
| To assess the linearity of the assay, samples were spiked with high concentrations of human CEACAM6 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. | ||||||
| Sample | Serum(n=4) | |||||
| 1:1 | Average % | 98 | ||||
| Range % | 92-104 | |||||
| 1:2 | Average % | 95 | ||||
| Range % | 91-99 | |||||
| 1:4 | Average % | 98 | ||||
| Range % | 92-103 | |||||
| 1:8 | Average % | 88 | ||||
| Range % | 80-92 | |||||
回收率：
| The recovery of human CEACAM6 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. | ||||||
| Sample Type | Average % Recovery | Range | ||||
| Serum (n=5) | 93 | 89-98 | ||||
| EDTA plasma (n=4) | 101 | 97-105 | ||||
标准曲线：
| These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. | ||||||
| ng/mlOD1OD2AverageCorrected 201.9051.9851.9451.909 101.3081.3681.3381.302 50.8410.8260.8340.798 1.670.3780.3870.3830.347 0.830.2140.2170.2160.180 00.0350.0360.036 | ||||||
货期：3-5 working days
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