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产品描述：人炭疽毒素受体2(ANTXR2)酶联免疫试剂盒为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的ANTXR2含量。ANTXR2即炭疽毒素受体2，在细胞外基质相互作用及组织发育中发挥作用。其作为炭疽毒素的结合位点被深入研究，在癌症领域也受关注，研究发现它在肿瘤血管生成中起作用，探索其机制有望为相关疾病治疗提供新思路。试剂盒检测范围为15.6 pg/mL-1000 pg/mL，在科研领域，本产品可用于探索炭疽毒素作用机制、受体功能研究、肿瘤微环境中宿主 - 病原体互作分析，以及动物模型中相关蛋白表达水平的动态监测，为感染性疾病、免疫调控及细胞信号通路研究提供可靠工具。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：ANTXR2; CMG2; Anthrax toxin receptor 2; Capillary morphogenesis gene 2 protein; CMG-2
缩写：ANTXR2
Uniprot No.：P58335
种属：Homo sapiens (Human)
样本类型：serum, plasma, tissue homogenates
检测范围：15.6 pg/mL-1000 pg/mL
灵敏度：3.9 pg/mL
反应时间：1-5h
样本体积：50-100ul
检测波长：450 nm
研究领域：Neuroscience
测定原理：quantitative
测定方法：Sandwich
精密度：
| Intra-assay Precision (Precision within an assay): CV%<8% | ||||||
| Three samples of known concentration were tested twenty times on one plate to assess. | ||||||
| Inter-assay Precision (Precision between assays): CV%<10% | ||||||
| Three samples of known concentration were tested in twenty assays to assess. | ||||||
线性度：
| To assess the linearity of the assay, samples were spiked with high concentrations of human ANTXR2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. | ||||||
| Sample | Serum(n=4) | |||||
| 1:1 | Average % | 95 | ||||
| Range % | 90-99 | |||||
| 1:2 | Average % | 90 | ||||
| Range % | 84-100 | |||||
| 1:4 | Average % | 92 | ||||
| Range % | 85-102 | |||||
| 1:8 | Average % | 92 | ||||
| Range % | 89-98 | |||||
回收率：
| The recovery of human ANTXR2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. | ||||||
| Sample Type | Average % Recovery | Range | ||||
| Serum (n=5) | 95 | 86-106 | ||||
| EDTA plasma (n=4) | 91 | 87-95 | ||||
标准曲线：
| These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. | ||||||
| pg/mlOD1OD2AverageCorrected10002.2932.3252.3092.1025001.6041.6291.6171.4102501.1421.1011.1220.9151250.6960.7110.7040.49762.50.4920.5030.4980.29131.20.3510.3620.3570.15015.60.2820.2710.2770.07000.2050.2080.207 | ||||||
货期：3-5 working days
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