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产品描述:小鼠血管内皮细胞粘附分子1(VCAM-1/CD106)酶联免疫试剂盒为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织培养上清液、组织匀浆样本中的VCAM1含量。VCAM1(血管细胞粘附分子1)是一种细胞表面糖蛋白,属于免疫球蛋白超家族。它主要在活化的内皮细胞表面表达,通过与白细胞表面的特定分子结合,调节炎症反应和白细胞迁移。VCAM1在免疫反应和炎症过程中发挥重要作用,其表达增加与多种免疫性疾病和癌症的进展密切相关。研究显示,VCAM1通过调节小胶质细胞的功能和Aβ的清除,在阿尔茨海默病的发生发展中扮演关键角色。试剂盒检测范围为39.062 pg/mL-2500 pg/mL,灵敏度为29.649 pg/mL。适用于体外研究血管内皮细胞活化状态、炎症反应机制、药物干预效果评估等科研领域,为心血管疾病、免疫调控及肿瘤微环境等领域的机制研究提供可靠工具。本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
别名:Vcam1; Vcam-1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; CD antigen CD106
缩写:VCAM1
Uniprot No.:P29533
种属:Mus musculus (Mouse)
样本类型:serum, plasma, cell culture supernates, tissue homogenates
检测范围:39.062 pg/mL-2500 pg/mL
灵敏度:29.649 pg/mL
反应时间:1-5h
样本体积:50-100ul
检测波长:450 nm
研究领域:Cardiovascular
测定原理:quantitative
测定方法:Sandwich
精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of mouse VCAM-1/CD106 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
货期:3-5 working days
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