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产品描述:人血管内皮细胞生长因子受体2(VEGFR-2/Flk-1)酶联免疫试剂盒为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的VEGFR-2/Flk-1含量。VEGFR-2/Flk-1是重要的血管内皮生长因子受体。在肿瘤等疾病中,其过度激活促使血管生成,为肿瘤提供营养。研究聚焦于抑制它来阻断血管生成信号通路,以抑制肿瘤生长、转移,相关抑制剂研发是肿瘤治疗研究热点。试剂盒检测范围为0.39 ng/mL-25 ng/mL,灵敏度为0.098 ng/mL。适用于探究血管生成机制、疾病模型中受体表达动态变化等科研场景;为研究肿瘤微环境、心血管病理机制或药物干预效果提供可靠工具,满足体外实验中对VEGFR - 2蛋白水平的定量分析需求。本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
别名:CD309 ELISA Kit; CD309 antigen ELISA Kit; EC 2.7.10.1 ELISA Kit; Fetal liver kinase 1 ELISA Kit; FLK-1 ELISA Kit; FLK1 ELISA Kit; FLK1, mouse, homolog of ELISA Kit; Kdr ELISA Kit; Kinase insert domain receptor (a type III receptor tyrosine kinase) ELISA Kit; Kinase insert domain receptor ELISA Kit; KRD1 ELISA Kit; Ly73 ELISA Kit; Protein tyrosine kinase receptor FLK1 ELISA Kit; Protein-tyrosine kinase receptor flk-1 ELISA Kit; soluble VEGFR2 ELISA Kit; Tyrosine kinase growth factor receptor ELISA Kit; Vascular endothelial growth factor receptor 2 ELISA Kit; VEGFR 2 ELISA Kit; VEGFR ELISA Kit; VEGFR-2 ELISA Kit; VEGFR2 ELISA Kit; VGFR2_HUMAN ELISA Kit
缩写:VEGFR2
Uniprot No.:P35968
种属:Homo sapiens (Human)
样本类型:serum, plasma, tissue homogenates
检测范围:0.39 ng/mL-25 ng/mL
灵敏度:0.098 ng/mL
反应时间:1-5h
样本体积:50-100ul
检测波长:450 nm
研究领域:Cardiovascular
测定原理:quantitative
测定方法:Sandwich
精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays):CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of human VEGFR-2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
本试剂盒所含材料:
VEGFR-2/Flk-1(血管内皮生长因子受体-2/胚胎血管成型蛋白-1)是血管内皮生长因子(VEGF)家族的成员之一,它参与了血管的生成和调节。最近的研究发现,VEGFR-2/Flk-1 除了在血管形成和肿瘤血管生成中发挥作用外,还与心血管疾病的发生和发展密切相关。例如,一些研究发现,VEGFR-2/Flk-1 在心肌缺血再灌注损伤中扮演着重要角色,而某些药物通过调节 VEGFR-2/Flk-1 的活性可以改善心肌缺血再灌注损伤。这些研究有望为心血管疾病的治疗和预防提供新的思路和方法。
货期:3-5 working days
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