关键信息
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基因名
CL-L1/COLEC10
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简介
CL-L1/COLEC10, operating as a lectin, displays distinct sugar-binding preferences, with a hierarchy of galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Apart from its sugar-binding role, CL-L1/COLEC10 functions as a chemoattractant, suggesting potential engagement in the modulation of cell migration. CL-L1/COLEC10 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CL-L1/COLEC10 protein, expressed by HEK293 , with N-hFc labeled tag.
- 应用
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生物活性
Immobilized Recombinant Human Integrin alpha X beta 2 Protein Protein at 5 µg/mL (100 µL/well) can bind Biotinylated Mouse CL-L1 protein. The ED50 for this effect is 2.839 μg/mL, corresponding to a specific activity is 352.237 Unit/mg. Immobilized Recombinant Human Integrin alpha X beta 2 Protein Protein at 5 µg/mL (100 µL/well) can bind Biotinylated Mouse CL-L1 protein. The ED50 for this effect is 2.839 μg/mL, corresponding to a specific activity is 352.237 Unit/mg.
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别名
Collectin-10; Collectin liver protein 1; CL-L1
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种属
Mouse
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表达系统
HEK293
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标签
N-hFc
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q8CF98
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表达区间
C119-K277
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蛋白长度
Partial
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分子量
53-57 kDa.
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CL-L1, also known as COLEC10, is a member of the collectin family of proteins, which play pivotal roles in the immune system by recognizing and binding to a variety of pathogens. These proteins are characterized by their collagen-like structure and lectin domains, enabling them to bind to carbohydrate structures on microbial surfaces. The study of CL-L1/COLEC10 is particularly significant due to its potential involvement in innate immune responses and its capacity to modulate inflammation and autoimmunity. Recent research has highlighted the role of CL-L1 in recognizing specific pathogens, contributing to pathogen clearance and influencing dendritic cell function, thereby bridging innate and adaptive immunity. Furthermore, variations in the expression of CL-L1/COLEC10 have been linked to certain diseases, including autoimmune disorders, making it a candidate for therapeutic interventions. Understanding the molecular structure and biological functions of CL-L1/COLEC10 is crucial for elucidating its role in immune defense and developing novel strategies for disease treatment, emphasizing the importance of ongoing research into this intriguing protein.
