| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Protein FAM26F, FAM26F, C6orf187 |
| Entrez GeneID | 441168 |
| WB Predicted band size | 34.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This FAM26F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human FAM26F. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是基于FAM26F相关研究的**假设性文献示例**(请注意，这些文献并非真实存在，仅供格式参考)：
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1. **文献名称**：*FAM26F modulates antiviral responses in dendritic cells via TRAF3 interaction*
**作者**：Smith J, et al. (2020)
**摘要**：本研究利用兔源FAM26F多克隆抗体，通过免疫共沉淀技术发现FAM26F与TRAF3蛋白相互作用，证实其在树突状细胞抗病毒干扰素通路中的关键作用，为自身免疫疾病机制提供新视角。
2. **文献名称**：*Monoclonal antibody development for FAM26F and its prognostic value in colorectal cancer*
**作者**：Zhang L, et al. (2018)
**摘要**：团队成功制备小鼠抗人FAM26F单克隆抗体，并通过免疫组化分析发现FAM26F在结直肠癌组织中低表达，且与患者生存率正相关，提示其作为潜在肿瘤标志物的可能性。
3. **文献名称**：*FAM26F ablation exacerbates inflammation in sepsis models*
**作者**：Lee S, et al. (2019)
**摘要**：通过FAM26F特异性抗体介导的基因敲低实验，发现FAM26F缺失会加剧脓毒症模型小鼠的全身炎症反应，表明其负向调控NF-κB信号通路的生理功能。
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**备注**：若需真实文献，建议通过PubMed或Google Scholar以“FAM26F antibody”或“FAM26F function”为关键词检索，并筛选涉及抗体开发、验证或功能研究的论文。部分研究可能间接提及抗体应用(如Western Blot验证蛋白表达)。
The FAM26F (Family with Sequence Similarity 26. Member F) protein is a relatively understudied molecule implicated in immune regulation and cellular signaling. Belonging to the FAM26 family, which includes genes conserved across vertebrates, FAM26F is thought to play roles in innate immunity, particularly in modulating cytokine responses and antiviral defenses. Studies suggest it may interact with membrane-associated proteins or act as a secreted factor, though its exact molecular mechanisms remain unclear. FAM26F is expressed in immune cells, including macrophages and dendritic cells, and its expression can be induced by pathogens or inflammatory stimuli, linking it to host defense pathways.
Antibodies targeting FAM26F have emerged as critical tools for elucidating its biological functions. These antibodies, often developed in rabbit or mouse models, enable detection of FAM26F in techniques like Western blotting, immunofluorescence, and immunohistochemistry. Research using these reagents has associated FAM26F with inflammatory diseases, viral infections (e.g., influenza, HIV), and autoimmune disorders, with some evidence suggesting it regulates NF-κB or interferon signaling. However, challenges persist in characterizing FAM26F due to its low basal expression and potential post-translational modifications. Ongoing studies aim to validate antibody specificity and explore FAM26F's therapeutic potential as a immune modulator or diagnostic marker.
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