| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | VCX1; VCXB1; VCX-B1; VCX10R; VCX-10r |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human VCX |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下为模拟生成的关于VCX抗体的参考文献示例(非真实文献，仅供格式参考)：
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1. **文献名称**: "Development of a Monoclonal Antibody Targeting VCX-A Protein for Male Infertility Diagnosis"
**作者**: Zhang L, et al.
**摘要**: 本研究报道了一种特异性识别VCX-A蛋白的单克隆抗体的开发。该抗体通过杂交瘤技术制备，验证了其在人类睾丸组织中的定位能力，并应用于无精症患者的精子发生异常检测，证实其作为诊断标志物的潜力。
2. **文献名称**: "VCX/Y Family Proteins in Sperm Maturation: Insights from Immunohistochemical Analysis"
**作者**: Tanaka K, et al.
**摘要**: 通过免疫组化技术，利用兔源多克隆VCX抗体分析VCX/Y蛋白家族在小鼠精子发生不同阶段的表达模式，揭示了其在染色质重塑中的作用，为男性生殖障碍机制研究提供依据。
3. **文献名称**: "Structural Characterization of VCX-B Protein Using Antibody-Based Epitope Mapping"
**作者**: Gupta R, et al.
**摘要**: 研究通过合成肽段免疫法制备多克隆抗体，结合Western blot和ELISA技术解析VCX-B蛋白的抗原表位，阐明其与X染色体连锁的蛋白结构特征及功能相关性。
4. **文献名称**: "VCX Antibody Cross-Reactivity Analysis in Primate Models"
**作者**: Smith J, et al.
**摘要**: 评估了商业化VCX抗体在非人类灵长类动物模型中的交叉反应性，发现部分抗体在猕猴睾丸组织中存在非特异性结合，提示抗体选择需谨慎，并提出了优化验证方案。
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注：以上文献为模拟生成，实际研究中请通过学术数据库(如PubMed、Web of Science)检索真实发表的论文。若需具体领域文献，建议补充VCX抗体的研究背景或目标应用方向。
VCX antibodies target proteins encoded by the Variable Charge, X-linked (VCX) gene family, which includes VCX, VCX2. VCX3A, and VCX3B. These genes are located on the X chromosome and are characterized by tandemly arranged, highly homologous sequences. VCX proteins are small, positively charged molecules primarily expressed in male germ cells during spermatogenesis, suggesting a role in sperm development and function. Their variable charge properties are attributed to repetitive amino acid motifs, which may influence interactions with nucleic acids or other cellular components.
The VCX gene family has garnered interest due to its involvement in X-linked intellectual disability (XLID) syndromes. Mutations or deletions in VCX genes, particularly VCX3A, have been linked to neurodevelopmental disorders, though the exact mechanisms remain unclear. VCX antibodies are essential tools for studying these proteins' expression patterns, subcellular localization, and functional roles in both reproductive and neurological contexts.
In research, VCX antibodies are employed in techniques like immunohistochemistry, Western blotting, and immunofluorescence to explore protein expression in tissues, notably the testis and brain. They also aid in investigating potential cross-talk between VCX proteins and other cellular pathways, including epigenetic regulation. Despite their specialized focus, VCX antibodies contribute broadly to understanding human fertility, genetic diseases, and X-chromosome biology.
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