Rabbit Polyclonal FTSJ3 Antibody

The FTSJ3 antibody is a research tool designed to detect and study the FTSJ3 protein, a member of the FtsJ RNA methyltransferase family. FTSJ3 (also known as METTL6) is implicated in RNA modification, specifically catalyzing the methylation of RNA molecules, which plays a regulatory role in RNA stability, processing, and translation. This protein is evolutionarily conserved and contains characteristic methyltransferase domains, suggesting its involvement in fundamental cellular processes. Studies have linked FTSJ3 to ribosome biogenesis, tRNA modification, and potential roles in cell proliferation and differentiation. Its dysregulation has been explored in contexts such as cancer, where abnormal RNA methylation patterns may contribute to tumorigenesis or disease progression. The FTSJ3 antibody enables researchers to investigate its expression levels, subcellular localization (primarily nucleolar), and interactions in various biological systems. It is commonly used in techniques like Western blotting, immunohistochemistry, and immunofluorescence. Current research focuses on elucidating FTSJ3's precise molecular mechanisms, its substrate specificity, and its potential as a biomarker or therapeutic target in human diseases.