| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Synaptotagmin-16; Synaptotagmin XIV-related protein; Synaptotagmin 14-like protein; Chr14Syt; SYT16 |
| Entrez GeneID | 83851; |
| WB Predicted band size | 72kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human SYT16. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于SYT16抗体的3篇假设性参考文献示例(请注意文献为虚构，仅供格式参考)：
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1. **文献名称**: "Synaptotagmin 16 regulates exocytosis in neuroendocrine cells"
**作者**: Smith A, et al.
**摘要**: 本研究利用特异性SYT16抗体，通过免疫印迹和免疫荧光技术，证实SYT16在神经内分泌细胞囊泡分泌中的关键作用，并发现其与钙离子通道的相互作用机制。
2. **文献名称**: "Development of a monoclonal antibody against human SYT16 for cancer biomarker studies"
**作者**: Chen B, et al.
**摘要**: 报道了一种高特异性SYT16单克隆抗体的开发，并验证其在乳腺癌组织样本中的诊断潜力，通过免疫组化证实SYT16在肿瘤细胞中的异常高表达。
3. **文献名称**: "SYT16 modulates neuronal dendritic growth via membrane trafficking"
**作者**: Lee C, et al.
**摘要**: 通过SYT16抗体的阻断实验，揭示了SYT16在神经元树突发育中的功能，表明其通过调控膜运输影响突触可塑性。
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如需真实文献，建议在PubMed或Google Scholar检索“SYT16 antibody”或“Synaptotagmin 16 antibody”，并筛选涉及抗体开发、验证或应用的论文。
The SYT16 antibody targets Synaptotagmin 16 (SYT16), a member of the synaptotagmin family of calcium-binding proteins involved in membrane trafficking and secretory processes. SYT16 is characterized by its tandem C2 domains, which mediate calcium-dependent interactions with phospholipids and SNARE complexes. While synaptotagmins like SYT1 are well-studied in neurotransmitter release, SYT16 has distinct roles, including regulating dense-core vesicle exocytosis in neuroendocrine cells and participating in cellular processes such as neurite outgrowth and receptor trafficking. SYT16 is also implicated in tissue-specific functions, such as acrosome formation in sperm and insulin secretion in pancreatic β-cells.
The SYT16 antibody is a critical tool for studying these diverse roles, enabling detection and localization of SYT16 in various models via techniques like Western blot, immunofluorescence, and immunohistochemistry. Recent studies highlight its relevance in neurological disorders, cancer (e.g., glioblastoma), and metabolic diseases, though its precise mechanisms remain under investigation. Researchers utilize this antibody to explore SYT16's interaction partners, post-translational modifications, and tissue-specific expression patterns, advancing understanding of its contribution to cellular physiology and disease pathways.
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