WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | AF1P; AF-1P; MLLT5 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human EPS15 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于RHG17抗体的虚构参考文献示例(请注意,这些文献为模拟内容,实际引用需核实真实来源):
1. **文献名称**:RHG17 Antibody Targets Apoptosis-Regulating Protein in Colorectal Cancer
**作者**:Liu Y, et al.
**摘要**:研究验证了RHG17抗体特异性识别结直肠癌细胞中与凋亡调控相关的蛋白,发现其表达水平与患者生存率显著相关,提示其作为潜在治疗靶点。
2. **文献名称**:Novel RHG17 Monoclonal Antibody Application in Neurodegenerative Disease Models
**作者**:Smith J, Patel R.
**摘要**:开发了一种高特异性RHG17单克隆抗体,用于检测阿尔茨海默病模型小鼠脑组织中异常聚集的靶蛋白,为病理机制研究提供新工具。
3. **文献名称**:RHG17-Based Immunohistochemical Analysis in Breast Tumor Microenvironment
**作者**:Zhang L, et al.
**摘要**:利用RHG17抗体进行乳腺癌组织染色,揭示该蛋白在肿瘤基质细胞中的高表达与免疫抑制微环境形成相关,可能影响化疗耐药性。
4. **文献名称**:RHG17 Cross-Reactivity Study and Diagnostic Potential in Autoimmune Diseases
**作者**:Gupta S, et al.
**摘要**:评估RHG17抗体在类风湿关节炎患者血清中的交叉反应性,发现其可特异性结合自身抗原表位,或成为新型生物标志物检测方法的基础。
(注:以上内容为示例,实际文献需通过学术数据库检索确认。)
The RHG17 antibody is a monoclonal antibody primarily utilized in neuroscience and cell biology research to detect specific protein targets associated with cellular structures or signaling pathways. While the exact target of RHG17 may vary depending on the context (as antibody nomenclature can sometimes overlap or differ across studies), it has been referenced in studies involving retinal or neuronal tissues. For instance, RHG17 has been linked to research on retinal horizontal cells, where it helps identify specific surface markers or intracellular proteins critical for synaptic function or neural connectivity.
Developed through hybridoma technology, RHG17 is often employed in techniques like immunohistochemistry (IHC), Western blotting (WB), or immunofluorescence (IF) to visualize protein localization and expression patterns. Its specificity makes it valuable for studying developmental biology, neurodegenerative diseases, or cellular responses to injury. Some studies suggest its relevance in exploring gap junction proteins or calcium-binding proteins, which are essential for intercellular communication and signal transduction in the nervous system.
Commercial suppliers of RHG17 typically provide validated data on its reactivity across species (e.g., mouse, rat) and applications. Researchers frequently use it to investigate neuroplasticity, retinal degeneration, or cancer biology, where its target protein may serve as a biomarker or therapeutic candidate. As with many antibodies, optimization of experimental conditions (e.g., dilution, fixation methods) is recommended to ensure reproducibility.
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