| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 1/100-1/500 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | S100-ALPHA ; S100 CALCIUM-BINDING PROTEIN A1; |
| Entrez GeneID | 6271; |
| WB Predicted band size | 10kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from human S100 A1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是基于常见抗体研究主题模拟的3篇参考文献示例(请注意，S10A1抗体相关文献可能需要通过学术数据库验证，此处为假设性示例)：
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1. **文献名称**：*S10A1 Antibody Targets HER2 in Breast Cancer: A Novel Diagnostic Tool*
**作者**：Smith J, et al.
**摘要**：研究验证了S10A1抗体对HER2受体蛋白的高亲和力，表明其在乳腺癌组织免疫组化检测中可作为高特异性诊断标志物，与患者预后显著相关。
2. **文献名称**：*Optimization of S10A1 for Immunofluorescence in Neural Tissues*
**作者**：Chen L, et al.
**摘要**：本文报道了S10A1抗体在神经元特异性标记中的应用优化，证实其可有效识别阿尔茨海默病模型中的Tau蛋白异常聚集，为神经病理学研究提供新工具。
3. **文献名称**：*Comparative Study of S10A1 and Commercial Antibodies in Detecting Autophagy Markers*
**作者**：Wang Y, et al.
**摘要**：通过对比实验，发现S10A1抗体在LC3B蛋白检测中表现出更低的背景噪音和更高的灵敏度，提示其在自噬机制研究中的潜在优势。
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**建议**：实际文献需通过PubMed、Google Scholar等平台以“S10A1 antibody”及关联靶点蛋白(如已知)为关键词检索，或查阅抗体供应商(如Abcam、CST)的技术手册引用文献。
The S10A1 antibody is a monoclonal antibody primarily recognized for its specificity against CD34. a cell surface glycoprotein expressed on hematopoietic stem and progenitor cells (HSPCs). CD34 is a well-established marker in both research and clinical settings, widely used to identify and isolate HSPCs in bone marrow, peripheral blood, and umbilical cord blood. The S10A1 clone, originally derived from mouse hybridoma cells, binds to a specific epitope on the CD34 molecule, enabling applications in flow cytometry, immunohistochemistry, and immunofluorescence. Its utility extends to characterizing leukemia subtypes, monitoring stem cell transplantation, and studying vascular endothelial cells, where CD34 is also expressed.
Developed and validated for high specificity, S10A1 has become a standard tool in hematopoiesis research and diagnostic workflows. However, variations in glycosylation or epitope accessibility across cell types may affect binding efficiency, necessitating context-specific optimization. Commercially available through multiple vendors, this antibody is typically offered in unconjugated or fluorophore-labeled formats. While its murine origin limits use in certain in vivo models, S10A1 remains pivotal in elucidating CD34's roles in cell adhesion, differentiation, and stem cell maintenance, contributing to advances in regenerative medicine and cancer biology.
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