Rabbit Polyclonal EPHA7(Ab-791) Antibody

The EPHA7 (Ab-791) antibody is a well-characterized tool for detecting EPHA7. a member of the Eph receptor tyrosine kinase family, which plays critical roles in cell-cell communication, tissue patterning, and disease processes. Eph receptors, including EPHA7. interact with membrane-bound ephrin ligands to regulate diverse biological functions such as cell migration, axon guidance, and angiogenesis. EPHA7 is particularly implicated in cancer biology, where it may act as a tumor suppressor or oncogene depending on cellular context, and in neurodevelopmental disorders. The Ab-791 antibody specifically recognizes an epitope within the extracellular domain of human EPHA7. enabling applications like Western blotting, immunohistochemistry, and immunofluorescence to study protein expression, localization, and post-translational modifications. Its validation in multiple experimental systems makes it valuable for investigating EPHA7's role in cellular signaling pathways, tumor progression, and tissue regeneration. Researchers frequently employ this antibody to explore EPHA7's dual functionality in both physiological processes and pathological conditions, including its emerging association with therapeutic resistance in certain cancers. Proper controls, such as EPHA7-knockout cell lines, are recommended to confirm specificity due to potential cross-reactivity with homologous Eph family members.