关键信息
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基因名
PTTG
- 应用
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别名
PTTG；EAP1；PTTG；TUTR1；Securin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95997
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表达区间
2-202aa
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氨基酸序列
ATLIYVDKE NGEPGTRVVA KDGLKLGSGP SIKALDGRSQ VSTPRFGKTF DAPPALPKAT RKALGTVNRA TEKSVKTKGP LKQKQPSFSA KKMTEKTVKA KSSVPASDDA YPEIEKFFPF NPLDFESFDL PEEHQIAHLP LSGVPLMILD EERELEKLFQ LGPPSPVKMP SPPWESNLLQ SPSSILSTLD VELPPVCCDI DI
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分子量
22.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The study of PTTG (Pituitary Tumor-Transforming Gene) recombinant proteins has gained significant attention in recent years due to their pivotal role in cell division and tumorigenesis. PTTG is a multifunctional protein initially identified for its overexpression in pituitary tumors, leading to its characterization as an oncogene. Its involvement in various cellular processes, including chromosomal segregation and the regulation of mitosis, underscores its importance in cancer biology. As a result, researchers have focused on the recombinant expression of PTTG to better understand its functional properties and to explore its potential as a therapeutic target. The recombinant proteins facilitate the investigation of PTTG’s mechanisms at a molecular level, enabling the elucidation of its interactions with other cellular components. Furthermore, examining the biochemical properties of PTTG can lead to the development of novel strategies for cancer treatment, particularly in tumors where PTTG is overexpressed. Additionally, understanding the pathways modulated by PTTG can provide insights into the mechanisms of tumor progression and resistance to therapies. Thus, ongoing research into PTTG recombinant proteins is essential for advancing our comprehension of tumor biology and the development of targeted therapeutic approaches.
