关键信息
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基因名
ITGB1BP3
- 应用
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别名
NMRK2;ITGB1BP3;NRK2;Nicotinamide riboside kinase 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NPI5
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表达区间
1-230aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMKLIVGI GGMTNGGKTT LTNSLLRALP NCCVIHQDDF FKPQDQIAVG EDGFKQWDVL ESLDMEAMLD TVQAWLSSPQ KFARAHGVSV QPEASDTHIL LLEGFLLYSY KPLVDLYSRR YFLTVPYEEC KWRRSTRNYT VPDPPGLFDG HVWPMYQKYR QEMEANGVEV VYLDGMKSRE ELFREVLEDI QNSLLNRSQE SAPSPARPAR TQGPGRGCGH RTARPAASQQ DSM
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分子量
28 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ITGB1BP3, also known as Integrin beta 1-binding protein 3, has garnered attention in recent years due to its crucial role in various biological processes, including cell adhesion, migration, and signaling. This protein is implicated in the regulation of integrin function, which is vital for maintaining tissue integrity and facilitating cellular interactions with the extracellular matrix. Research has indicated that ITGB1BP3 may have significant implications in cancer biology, as alterations in its expression can affect tumor progression and metastasis. Furthermore, its involvement in cellular processes such as apoptosis and differentiation positions ITGB1BP3 as a potential biomarker for various diseases, as well as a target for therapeutic interventions. The recombinant protein form of ITGB1BP3 allows for detailed studies of its structure and function, enabling researchers to elucidate its mechanisms of action and explore its potential in drug development. Understanding the biochemical properties and interactions of ITGB1BP3 is essential not only for expanding our knowledge of integrin-related pathways but also for uncovering its relevance in pathological conditions.
