Rabbit Polyclonal CF150 Antibody

The CF150 antibody is a monoclonal antibody primarily developed to target specific epitopes associated with cytoskeletal or intracellular proteins, often used in cellular and molecular biology research. While the exact antigen may vary depending on the study, CF150-class antibodies are commonly linked to intermediate filament proteins, such as nestin or vimentin, which play roles in cell structure, motility, and differentiation. These antibodies gained prominence in neurobiology and oncology for identifying stem/progenitor cells or characterizing tumor cell phenotypes. For instance, nestin-targeting CF150 antibodies have been utilized to label neural stem cells in developmental studies or to detect cancer stem cells in glioblastoma research. Their application spans immunohistochemistry, immunofluorescence, and Western blotting, aiding in visualizing cellular morphology and protein localization. The development of CF150-class antibodies reflects the growing need for tools to explore cell plasticity, tumor heterogeneity, and regenerative mechanisms. However, specificity validation remains critical, as cross-reactivity with unrelated epitopes can occur. Researchers often employ these antibodies alongside other markers to confirm cell identity or functional states. Their utility in both basic and translational research underscores their importance in advancing understanding of cellular dynamics in health and disease.