Rabbit Polyclonal C12orf56(N-term) Antibody

The C12orf56 (N-term) antibody is a research tool designed to target the N-terminal region of the protein encoded by the C12orf56 gene, located on human chromosome 12. This gene, also known as FAM83H or family with sequence similarity 83 member H, has been implicated in various cellular processes, though its precise biological function remains under investigation. The encoded protein is thought to play roles in cell adhesion, signaling pathways, and possibly cancer progression, with studies linking its dysregulation to malignancies like colorectal and breast cancers. The N-terminal-specific antibody enables researchers to study the protein’s expression, localization, and interactions in different experimental models, such as Western blotting, immunohistochemistry, or immunofluorescence. Its development often involves immunizing hosts with synthetic peptides or recombinant protein fragments corresponding to the N-terminal domain, followed by affinity purification. Validation typically includes testing in knockout cell lines or tissues to confirm specificity. This antibody is particularly valuable in exploring C12orf56’s involvement in disease mechanisms or normal physiology, aiding efforts to clarify its molecular interactions and potential as a therapeutic target. Commercial versions may vary in clonality (monoclonal/polyclonal) and host species (e.g., rabbit, mouse). Researchers should optimize protocols for specific applications to ensure reproducibility.