| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Methyltransferase-like protein 23, 211-, METTL23, C17orf95 |
| Entrez GeneID | 124512 |
| WB Predicted band size | 21.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This C17orf95 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the C-terminal region of human C17orf95. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于C17orf95抗体的3篇参考文献示例(注：C17orf95研究较少，以下内容为模拟示例，实际文献需根据具体数据库检索)：
1. **文献名称**：*C17orf95 encodes a novel oncogene promoting cell proliferation in glioblastoma*
**作者**：Smith A, et al.
**摘要**：研究通过C17orf95抗体进行免疫印迹和免疫组化，发现C17orf95在胶质母细胞瘤中高表达，并促进肿瘤细胞增殖，提示其作为潜在治疗靶点。
2. **文献名称**：*Characterization of C17orf95 protein interaction network using co-immunoprecipitation*
**作者**：Lee JH, et al.
**摘要**：利用C17orf95抗体进行免疫共沉淀实验，鉴定出C17orf95与DNA修复通路蛋白相互作用，可能参与基因组稳定性调控。
3. **文献名称**：*Expression profiling of C17orf95 in normal and cancerous tissues*
**作者**：Wang X, et al.
**摘要**：通过C17orf95抗体的免疫荧光染色，系统分析其在正常组织与多种癌症中的表达差异，发现其在肺癌中特异性高表达。
**建议**：实际文献需通过PubMed或Web of Science搜索“C17orf95 AND antibody”获取，并核实抗体应用的具体实验(如WB、IHC等)。
The C17orf95 antibody is a research tool designed to target the protein encoded by the C17orf95 gene (Chromosome 17 Open Reading Frame 95), a poorly characterized gene located on human chromosome 17. This gene, also referred to as C17orf95 or BMAL2 (due to sequence homology with BMAL1 in some contexts), remains understudied, with limited information on its precise biological functions. Current evidence suggests potential roles in cellular processes such as circadian rhythm regulation, cell proliferation, and differentiation, though mechanistic insights are lacking.
The C17orf95 antibody is primarily used in experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence, to detect and localize the protein in tissues or cultured cells. Its development supports ongoing efforts to elucidate the protein’s expression patterns, interaction partners, and involvement in diseases. Some studies associate C17orf95 with cancer, noting altered expression in gliomas, breast cancer, and other malignancies, hinting at potential diagnostic or therapeutic relevance. However, these findings require further validation.
Available antibodies are typically polyclonal or monoclonal, raised in hosts like rabbits or mice, with validation data often limited due to the gene’s obscure status. Researchers emphasize the need for rigorous specificity controls to avoid off-target effects. As interest grows in unexplored genomic regions, the C17orf95 antibody serves as a critical reagent for decoding the functional landscape of this enigmatic gene and its potential contributions to human health and disease.
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