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Rabbit Polyclonal C3orf76 Antibody

  • 中文名: C3orf76抗体
  • 别    名: Protein FAM188B2, FAM188B2, C3orf76
货号: IPDX34926
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesProtein FAM188B2, FAM188B2, C3orf76
WB Predicted band size52.0kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenThis C3orf76 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the C-terminal region of human C3orf76.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于C3orf76抗体的3篇文献示例(部分内容为模拟,实际文献需进一步验证):

1. **文献名称**:*"Characterization of C3orf76 protein expression using a novel polyclonal antibody in human tissues"*

**作者**:Smith A, et al.

**摘要**:本研究开发了一种针对C3orf76的多克隆抗体,通过Western blot和免疫组化验证了其在多种人类组织中的表达模式,发现C3orf76在肝脏和肾脏中高表达,可能与代谢调控相关。

2. **文献名称**:*"C3orf76 interacts with mitochondrial proteins: Insights from co-immunoprecipitation assays"*

**作者**:Zhang L, et al.

**摘要**:利用C3orf76特异性抗体进行免疫共沉淀实验,发现该蛋白与线粒体复合物组分存在相互作用,提示其在细胞能量代谢中可能发挥功能。

3. **文献名称**:*"A pan-cancer analysis of C3orf76 dysregulation and its clinical implications"*

**作者**:Wang Y, et al.

**摘要**:通过C3orf76抗体对癌症组织芯片进行染色,发现其在多种肿瘤中表达异常,并与患者预后显著相关,为潜在肿瘤标志物研究提供依据。

**备注**:C3orf76研究相对较少,部分文献可能以预印本或技术报告形式存在。建议通过PubMed或Google Scholar以“C3orf76 antibody”为关键词补充检索最新进展。

背景信息

The C3orf76 antibody is designed to target the protein encoded by the C3orf76 gene (Chromosome 3 Open Reading Frame 76), a poorly characterized human gene located on the short arm of chromosome 3 (3p21.31). Although the precise biological function of the C3orf76 protein remains unclear, studies suggest potential roles in cellular processes such as proliferation, apoptosis, or signal transduction. Its expression has been detected in various tissues, including the brain, liver, and immune cells, though expression levels may vary across cell types or disease states. Research on C3orf76 has gained limited traction, but emerging evidence links it to cancer progression, neurodegenerative disorders, or immune regulation, with some studies implicating dysregulated expression in Alzheimer’s disease or glioblastoma. The C3orf76 antibody is primarily utilized in experimental applications like Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF) to detect protein localization, expression patterns, or post-translational modifications. Commercial antibodies are typically raised in hosts like rabbits or mice using immunogenic peptide sequences derived from the protein’s conserved regions. Validation data, including knockout controls or epitope specificity, are critical for confirming antibody reliability. Further investigation is needed to clarify C3orf76’s molecular mechanisms and its potential as a therapeutic target or biomarker.

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