关键信息
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基因名
CK9
- 应用
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别名
CK9；C11orf15；Transmembrane Protein 9B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NQ34
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表达区间
1-198aa
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氨基酸序列
MATLWGGLLRLGSLLSLSCLALSVLLLAQLSDAAKNFEDVRCKCICPPYKENSGHIYNKNISQKDCDCLHVVEPMPVRGPDVEAYCLRCECKYEERSSVTIKVTIIIYLSILGLLLLYMVYLTLVEPILKRRLFGHAQLIQSDDDIGDHQPFANAHDVLARSRSRANVLNKVEYAQQRWKLQVQEQRKSVFDRHVVLS
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分子量
22.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The study of CK9 recombinant protein is rooted in the broader field of molecular biology and protein engineering, focusing on the significance of cytokeratins in cellular structure and function. Cytokeratin 9, specifically, is a type of intermediate filament protein predominantly expressed in the epithelial tissues of the skin and various organ systems. Its role as a structural component contributes to mechanical resilience and cellular integrity, making it crucial for maintaining tissue architecture. Research into CK9 is particularly important in understanding skin disorders, as mutations or malfunctions of cytokeratins can lead to various dermatological conditions, including palmoplantar keratoderma and epithelial tumors. By utilizing recombinant DNA technology, scientists aim to produce CK9 in a controlled manner, allowing for detailed studies of its structure-function relationships. This has implications not only for basic science but also for potential therapeutic applications, such as developing biomaterials for wound healing or targeted treatments for skin-related diseases. Overall, research on CK9 recombinant protein offers valuable insights into epithelial biology, disease mechanisms, and innovative therapeutic strategies.
