Rabbit Polyclonal DSUMO Antibody

The D SUMO antibody is a specialized tool used to detect SUMO (Small Ubiquitin-like Modifier) proteins in *Drosophila melanogaster*, a model organism widely employed in genetic and cellular studies. SUMO proteins are post-translational modifiers that regulate diverse processes such as transcriptional regulation, DNA repair, nuclear transport, and stress responses by covalently attaching to target proteins (SUMOylation). In *Drosophila*, SUMOylation plays critical roles in development, neuronal function, and immune responses. The D SUMO antibody specifically recognizes SUMO isoforms in *Drosophila*, enabling researchers to study SUMO dynamics in fly tissues or cell lines. It is commonly used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to map SUMOylation sites, identify interacting partners, or analyze SUMO-related pathways. Given the evolutionary conservation of SUMO pathways, findings in *Drosophila* often provide insights into analogous mechanisms in mammals, including humans. The antibody’s specificity and reliability are validated through knockout controls or peptide competition assays, ensuring accurate detection. Its applications span fundamental research on cell cycle regulation, stress signaling, and developmental biology, as well as disease models exploring SUMO dysregulation in neurodegeneration or cancer. The D SUMO antibody thus serves as a key reagent in dissecting the complexity of post-translational regulation in a genetically tractable organism.