| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 1B1, Olfactory receptor 9-B, OR9-B, Olfactory receptor OR9-26, OR1B1 |
| Entrez GeneID | 347169 |
| WB Predicted band size | 35.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR1B1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-183 amino acids from the Central region of human OR1B1. |
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以下是关于OR1B1抗体的模拟参考文献示例(注：文献为虚构示例，实际文献需通过学术数据库检索确认)：
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1. **文献名称**：*Olfactory Receptor OR1B1 Expression in Human Liver and Its Role in Lipid Metabolism*
**作者**：Smith, J. et al.
**摘要**：本研究通过免疫组化及Western blot技术，利用特异性OR1B1抗体证实了该嗅觉受体在人类肝细胞中的表达，并发现其可能通过调节脂质代谢相关基因影响肝脏功能。
2. **文献名称**：*Development of a Monoclonal Antibody for OR1B1 and Its Application in Prostate Cancer Detection*
**作者**：Zhang, L. et al.
**摘要**：作者开发了一种高灵敏度的OR1B1单克隆抗体，验证了其在前列腺癌组织中的特异性结合能力，提示OR1B1可能作为肿瘤标志物的潜在价值。
3. **文献名称**：*OR1B1 Antibody-Based Screening Reveals Ectopic Expression in Chronic Rhinosinusitis*
**作者**：Kim, H. et al.
**摘要**：通过OR1B1抗体检测慢性鼻窦炎患者鼻息肉样本，发现该受体在炎症组织中异常高表达，推测其可能参与局部免疫反应调控。
4. **文献名称**：*Characterization of a Polyclonal OR1B1 Antibody for Olfactory Receptor Functional Studies*
**作者**：Garcia, R. et al.
**摘要**：研究报道了一种多克隆OR1B1抗体的制备与验证，证明其可用于流式细胞术和共聚焦显微成像，为嗅觉受体信号通路研究提供工具。
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建议通过PubMed、Google Scholar等平台以“OR1B1 antibody”或“OR1B1 olfactory receptor”为关键词检索真实文献。
The OR1B1 antibody is a specialized tool used to detect and study the olfactory receptor 1B1 (OR1B1), a member of the olfactory receptor (OR) family, which constitutes the largest group of G protein-coupled receptors (GPCRs). ORs are critical for detecting odorant molecules and mediating the sense of smell. OR1B1. encoded by the OR1B1 gene, is expressed in olfactory sensory neurons within the nasal epithelium. Though its specific ligand and precise physiological role remain under investigation, OR1B1 is believed to contribute to odorant recognition and signal transduction, a process involving cAMP-mediated pathways.
Antibodies targeting OR1B1 are typically developed in immunized hosts (e.g., rabbits or mice) using peptide antigens derived from the receptor’s unique sequences. These antibodies enable researchers to localize OR1B1 expression in tissues via techniques like immunohistochemistry (IHC) or Western blotting, aiding studies on olfactory receptor distribution, regulation, and function. OR1B1-specific antibodies are also valuable in exploring potential non-olfactory roles of ORs, such as in metabolic processes or disease states, including cancer and neurological disorders. However, challenges like receptor heterogeneity and low endogenous expression levels necessitate rigorous validation of antibody specificity. Overall, OR1B1 antibodies serve as essential reagents for unraveling the complexity of olfactory signaling and broader GPCR biology.
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