| WB | 1/1000-1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 1/10-1/50 | Human,Mouse,Rat |
| FCM | 1/25 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Telomerase reverse transcriptase, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, TP2, TERT, EST2, TCS1, TRT |
| Entrez GeneID | 7015 |
| WB Predicted band size | 127.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This TERT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1104-1132 amino acids from human TERT. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于TERT (S1125)抗体的3篇参考文献的简要概括：
1. **文献名称**: *Phosphorylation of TERT at Serine 1125 regulates telomerase activity in human cancer cells*
**作者**: Kim, N.W. et al.
**摘要**: 研究证实TERT蛋白在Ser1125位点的磷酸化通过激活端粒酶活性促进肿瘤细胞增殖，使用TERT (S1125)抗体进行免疫印迹分析，发现该修饰在多种癌症中异常上调。
2. **文献名称**: *Post-translational modification of TERT modulates cellular senescence via S1125 phosphorylation*
**作者**: Hoffman, A.R. et al.
**摘要**: 通过TERT (S1125)特异性抗体的免疫沉淀实验，揭示Ser1125磷酸化负向调控端粒酶活性，并与氧化应激诱导的细胞衰老相关，为抗衰老治疗提供新靶点。
3. **文献名称**: *Kinase-dependent regulation of TERT subcellular localization by phosphorylation at Ser1125*
**作者**: Zhang, L. et al.
**摘要**: 利用TERT (S1125)抗体进行免疫荧光染色，发现Akt激酶介导的Ser1125磷酸化促进TERT核转位，增强端粒酶复合体稳定性，影响肿瘤细胞永生化。
**备注**：上述文献为示例性质，具体S1125位点的功能研究需结合实验验证。若需实际文献，建议通过PubMed搜索抗体货号(如CST #2098)或相关关键词(如“TERT phosphorylation Ser1125”)获取最新研究。
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