| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Synaptojanin-2-binding protein, Mitochondrial outer membrane protein 25, SYNJ2BP, OMP25 |
| Entrez GeneID | 55333 |
| WB Predicted band size | 15.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This SYNJ2BP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 22-66 amino acids from human SYNJ2BP. |
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以下是关于SYNJ2BP (N-Term)抗体的3篇参考文献示例(内容为虚构，供参考)：
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1. **文献名称**：*SYNJ2BP interacts with mitochondrial proteins to regulate oxidative stress response*
**作者**：Zhang L, et al.
**摘要**：该研究利用SYNJ2BP (N-Term)抗体验证了SYNJ2BP与线粒体复合物蛋白的相互作用，表明其在氧化应激调控中的关键作用。
2. **文献名称**：*Characterization of SYNJ2BP antibody for detecting neuronal synaptic plasticity markers*
**作者**：Smith J, et al.
**摘要**：通过SYNJ2BP (N-Term)抗体的免疫沉淀实验，揭示了SYNJ2BP在神经元突触可塑性中与突触蛋白的动态结合机制。
3. **文献名称**：*SYNJ2BP N-terminal domain mediates its role in cancer cell migration*
**作者**：Wang Y, et al.
**摘要**：研究使用SYNJ2BP (N-Term)特异性抗体，发现其通过调控细胞骨架重排促进肿瘤细胞迁移，为癌症治疗提供潜在靶点。
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如需真实文献，建议通过PubMed或Google Scholar搜索关键词“SYNJ2BP antibody N-terminal”获取最新研究。
The SYNJ2BP (Synaptojanin-2 Binding Protein) antibody targets the N-terminal region of the SYNJ2BP protein, a ubiquitously expressed adaptor protein involved in diverse cellular processes. SYNJ2BP, also known as PAN or PDZGEF2. interacts with Synaptojanin-2. a polyphosphoinositide phosphatase, to regulate membrane trafficking, cytoskeletal dynamics, and mitochondrial function. It localizes to the outer mitochondrial membrane and plays roles in mitochondrial morphology, apoptosis, and cell adhesion by mediating integrin signaling pathways. The N-terminal domain of SYNJ2BP is critical for its interaction with Synaptojanin-2 and other binding partners, influencing cellular responses to oxidative stress and metabolic regulation.
The SYNJ2BP (N-Term) antibody is widely used in research to detect endogenous SYNJ2BP expression via techniques like Western blotting, immunohistochemistry, and immunofluorescence. Its specificity for the N-terminal region ensures recognition of full-length SYNJ2BP, aiding studies on its subcellular localization, protein-protein interactions, and functional roles in diseases such as cancer, neurodegenerative disorders, and cardiovascular conditions. Validation data, including knockout controls or peptide blocking, are essential to confirm antibody specificity. Research using this antibody has contributed to understanding SYNJ2BP's involvement in mitochondrial dynamics, cell migration, and signaling crosstalk in pathological contexts.
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