Rabbit Polyclonal CCDC144A Antibody

The CCDC144A antibody is a research tool designed to detect the coiled-coil domain-containing protein 144A (CCDC144A), a poorly characterized protein encoded by the *CCDC144A* gene. This protein is predicted to play roles in cellular processes involving cytoskeletal organization or intracellular transport due to its structural domains, though its exact biological function remains unclear. CCDC144A has been loosely associated with cilia-related functions and reproductive biology, with some studies suggesting its involvement in spermatogenesis or ciliopathies. The antibody is primarily used in experimental settings, such as Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF), to map CCDC144A's expression patterns, subcellular localization, and potential interactions. Commercial CCDC144A antibodies are typically polyclonal or monoclonal, raised in hosts like rabbits or mice, and require validation for specificity due to limited literature. Recent interest in CCDC144A has emerged in cancer research, particularly in exploring its differential expression in tumors, though conclusive evidence linking it to oncogenic pathways is lacking. Researchers utilize this antibody to investigate its hypothetical roles in cellular signaling, structural integrity, or disease mechanisms, aiming to clarify its physiological relevance and therapeutic potential.