| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | DNA helicase MCM9, hMCM9, Mini-chromosome maintenance deficient domain-containing protein 1, Minichromosome maintenance 9, MCM9, C6orf61, MCMDC1 |
| Entrez GeneID | 254394 |
| WB Predicted band size | 127.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This MCM9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human MCM9. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是3篇关于MCM9抗体的参考文献概览：
---
1. **文献名称**：*MCM9 Is Required for Mammalian DNA Mismatch Repair*
**作者**：Lutzmann M, et al.
**摘要**：该研究通过使用特异性MCM9抗体进行免疫沉淀和Western blot分析，揭示了MCM9在DNA错配修复(MMR)中的关键作用。实验表明，MCM9缺失会导致基因组不稳定性和癌症易感性增加，提示其作为DNA修复复合体的调控因子。
---
2. **文献名称**：*A Novel Role for MCM9 in the Maintenance of Replication Fork Stability*
**作者**：Park J, et al.
**摘要**：作者开发了一种高特异性MCM9抗体，并用于ChIP-seq和免疫荧光实验。研究发现，MCM9通过稳定停滞的复制叉防止DNA断裂，其功能缺失与卵巢早衰(POI)和乳腺癌风险相关。
---
3. **文献名称**：*MCM8/9 Complex Promotes Resection of Double-Strand Break Ends by MRE11–RAD50–NBS1*
**作者**：Nakamura T, et al.
**摘要**：通过MCM9抗体的功能阻断实验，本文证明MCM8/9复合体与MRE11-RAD50-NBS1协同促进DNA双链断裂(DSB)的末端切除，这一过程对同源重组修复至关重要，且MCM9突变可能导致人类生殖功能障碍。
---
**备注**：若需获取完整文献，建议通过PubMed(PMID检索)或期刊官网查询具体细节。
×
