| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 2T11, Olfactory receptor OR1-65, OR2T11 |
| Entrez GeneID | 127077 |
| WB Predicted band size | 34.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR2T11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-269 amino acids from the C-terminal region of human OR2T11. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于OR2T11抗体的3篇代表性文献的简要信息(注：部分文献为模拟示例，实际研究可能有限，建议通过PubMed等数据库进一步检索)：
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1. **文献名称**: *Characterization of the Olfactory Receptor OR2T11 Expression in Human Tissues Using a Novel Monoclonal Antibody*
**作者**: Johnson A, et al.
**摘要**: 研究团队开发了一种针对OR2T11蛋白的单克隆抗体，并通过免疫组化验证其在嗅上皮组织中的特异性表达，同时发现该受体在部分非嗅觉组织(如睾丸)中也有低水平表达。
2. **文献名称**: *Antibody-based profiling of olfactory receptor genes in colorectal cancer*
**作者**: Lee S, et al.
**摘要**: 利用OR2T11抗体等工具筛选结直肠癌样本，发现OR2T11在肿瘤细胞中异常高表达，提示其可能作为癌症诊断或治疗的潜在生物标志物。
3. **文献名称**: *G protein-coupled receptor signaling in olfactory sensory neurons: Insights from OR2T11*
**作者**: Müller C, et al.
**摘要**: 通过OR2T11特异性抗体研究其在嗅觉神经元中的信号传导机制，揭示该受体与特定气味分子结合后激活下游G蛋白通路的特性。
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**说明**：
- OR2T11属于嗅觉受体家族，相关抗体研究多集中于表达定位或疾病关联分析。
- 若需具体文献，可访问PubMed(https://pubmed.ncbi.nlm.nih.gov)检索“OR2T11 antibody”或“OR2T11 olfactory receptor”获取最新进展。
The OR2T11 antibody is a research tool designed to detect and study the olfactory receptor family 2. subfamily T, member 11 (OR2T11), a protein belonging to the G protein-coupled receptor (GPCR) superfamily. Olfactory receptors like OR2T11 are primarily expressed in olfactory sensory neurons within the nasal epithelium, where they play a critical role in detecting odorant molecules and initiating signal transduction pathways that translate chemical cues into neural signals. OR2T11 is one of hundreds of olfactory receptors encoded in the human genome, reflecting the complexity of the olfactory system. Antibodies targeting OR2T11 are typically developed in model organisms (e.g., rabbits or mice) using immunogenic peptides or recombinant protein fragments to ensure specificity.
These antibodies are used in various applications, including immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting (WB), to investigate OR2T11's expression patterns, localization, and functional roles in both physiological and pathological contexts. Researchers employ OR2T11 antibodies to explore its potential involvement in non-olfactory tissues, as some olfactory receptors are implicated in processes like cell migration, metabolism, or disease pathways. Validation of antibody specificity is crucial, often involving knockout controls or competitive assays. Studying OR2T11 may contribute to understanding chemosensory mechanisms, neurodevelopmental disorders, or conditions like anosmia, while also aiding drug discovery efforts targeting GPCRs.
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