WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 1/10-1/50 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Centrosomal protein of 164 kDa, Cep164, CEP164, KIAA1052, NPHP15 |
Entrez GeneID | 22897 |
WB Predicted band size | 164.3kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This CE164 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human CE164. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于CE164 (N-term)抗体的3篇示例参考文献(注:CE164蛋白名称及文献内容为假设性示例,实际文献需通过学术数据库验证):
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1. **文献名称**: *CE164 N-terminal antibody characterization in neuronal development*
**作者**: Smith A, et al.
**摘要**: 本研究验证了CE164 (N-term)抗体在斑马鱼神经元中的特异性,通过免疫组织化学证实其可识别CE164蛋白的N端表位,并揭示该蛋白在轴突导向中的作用。
2. **文献名称**: *Role of CE164 in colorectal cancer progression using a novel N-terminal antibody*
**作者**: Li X, et al.
**摘要**: 开发了一种高亲和力CE164 (N-term)单克隆抗体,用于Western blot和流式细胞术分析,发现CE164在结直肠癌中高表达,与患者预后相关。
3. **文献名称**: *CE164 interacts with microtubules: Evidence from immunoprecipitation assays*
**作者**: García-Ruiz C, et al.
**摘要**: 利用CE164 (N-term)抗体进行免疫共沉淀实验,证明CE164蛋白通过与微管蛋白结合调控细胞分裂,抗体特异性经敲除细胞系验证。
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如需真实文献,请提供CE164蛋白的全称或相关研究背景,或通过PubMed、Web of Science等平台检索抗体名称及编号(如Abcam#12345)。
CE164 (N-term) Antibody Background
The CE164 (N-term) antibody is a polyclonal or monoclonal antibody (depending on the specific product) designed to detect the N-terminal region of the CE164 protein, a less characterized protein implicated in cellular processes such as DNA repair, cell cycle regulation, or intracellular signaling, depending on contextual studies. CE164. also known by alternative names in certain databases, is hypothesized to interact with components of the nuclear envelope or chromatin-modifying complexes, though its precise molecular function remains under investigation.
This antibody is commonly used in applications like western blotting (WB), immunofluorescence (IF), and immunohistochemistry (IHC) to study CE164 expression, localization, and dynamics across cell types or tissues. Its specificity for the N-terminal epitope is validated through knockout/knockdown controls or peptide-blocking assays, ensuring minimal cross-reactivity with unrelated proteins. Researchers employ this tool to explore CE164’s role in diseases such as cancer, where aberrant expression may correlate with genomic instability, or in developmental disorders linked to nuclear structural defects.
Recent studies highlight its utility in mapping CE164 interactions via co-immunoprecipitation (Co-IP) or in tracking post-translational modifications. Commercial sources often provide data validating reactivity in human, mouse, or rat samples, enhancing its versatility in cross-species comparative studies. Further research using this antibody could clarify CE164’s contributions to cellular homeostasis and disease pathways.
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