| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 6C4, Olfactory receptor OR12-10, OR6C4 |
| Entrez GeneID | 341418 |
| WB Predicted band size | 35.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR6C4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-270 amino acids from the C-terminal region of human OR6C4. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于OR6C4抗体的模拟参考文献示例(注：部分文献为假设性示例，实际检索请通过学术数据库验证)：
1. **文献名称**: *OR6C4 Olfactory Receptor Expression in Human Tissues and Its Antibody Validation*
**作者**: Smith A, et al.
**摘要**: 本研究通过免疫组化技术验证了OR6C4抗体(克隆号：AB123)的特异性，发现OR6C4在鼻黏膜和前列腺组织中高表达，可能参与化学信号感知。
2. **文献名称**: *Development of Monoclonal Antibodies Targeting OR6C4 for Cancer Biomarker Studies*
**作者**: Lee H, et al.
**摘要**: 开发了针对OR6C4的单克隆抗体，并证明其在结直肠癌组织中异常表达，提示其作为潜在生物标志物的可能性。
3. **文献名称**: *GPCR Antibody Characterization: A Case Study on OR6C4*
**作者**: Garcia R, et al.
**摘要**: 系统评估了OR6C4抗体的交叉反应性，确认其与OR6C家族其他成员的区分能力，为嗅觉受体功能研究提供可靠工具。
4. **文献名称**: *OR6C4 in Metabolic Regulation: Antibody-Based Detection Challenges*
**作者**: Chen L, et al.
**摘要**: 探讨了OR6C4在脂肪组织中的表达及其与代谢疾病的相关性，同时分析了商用抗体的灵敏度限制及优化策略。
**注意**：以上文献为示例性质，实际研究中请通过PubMed、Google Scholar等平台检索最新文献。若需具体文献协助，建议提供数据库访问权限或进一步检索关键词。
The OR6C4 antibody is designed to target olfactory receptor family 6 subfamily C member 4 (OR6C4), a protein encoded by the OR6C4 gene. Olfactory receptors (ORs), traditionally associated with odorant detection in the nasal epithelium, are G protein-coupled receptors (GPCRs) that initiate signal transduction upon ligand binding. Emerging research, however, reveals their expression in non-olfactory tissues, suggesting broader physiological roles. OR6C4. in particular, has been detected in the gastrointestinal tract, prostate, and other organs, though its specific ligands and functions remain poorly characterized.
Antibodies against OR6C4 are primarily used as research tools to investigate its localization, expression patterns, and potential involvement in diseases. For example, studies suggest OR6C4 may play a role in colorectal cancer progression, where its dysregulation correlates with tumorigenesis. These antibodies enable techniques like immunohistochemistry (IHC), Western blotting (WB), or flow cytometry to explore OR6C4's interaction networks and signaling pathways. Challenges include the low endogenous expression of OR6C4 in many tissues and the need for rigorous validation to ensure specificity. Despite limited functional data, OR6C4 antibodies hold promise for uncovering novel roles of olfactory receptors in cellular processes beyond sensory perception, potentially identifying therapeutic targets or biomarkers for disease.
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