关键信息
-
基因名
KRT33A
- 应用
-
别名
KRT33A；HHA3-I；HKA3A；KRTHA3A；Keratin. type I cuticular Ha3-I
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O76009
-
表达区间
1-404aa
-
氨基酸序列
MSYSCGLPSL SCRTSCSSRP CVPPSCHGCT LPGACNIPAN VSNCNWFCEG SFNGSEKETM QFLNDRLASY LEKVRQLERD NAELENLIRE RSQQQEPLVC ASYQSYFKTI EELQQKILCS KSENARLVVQ IDNAKLASDD FRTKYETELS LRQLVESDIN GLRRILDELT LCRSDLEAQV ESLKEELLCL KQNHEQEVNT LRCQLGDRLN VEVDAAPTVD LNQVLNETRS QYEALVETNR REVEQWFATQ TEELNKQVVS SSEQLQSYQA EIIELRRTVN ALEIELQAQH NLRDSLENTL TESEARYSSQ LSQVQRLITN VESQLAEIRS DLERQNQEYQ VLLDVRARLE CEINTYRSLL ESEDCKLPSN PCATTNACDK STGPCISNPC GLRARCGPCN TFGY
-
分子量
45.9 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
KRT33A, a type of cytokeratin protein, belongs to the keratin family, which plays a crucial role in the structural integrity and function of epithelial tissues. Research into KRT33A has gained attention due to its potential involvement in various biological processes and diseases, particularly in skin disorders and epithelial tumors. Cytokeratins, including KRT33A, are essential for maintaining the mechanical stability of cells and tissues, and aberrations in their expression can be indicative of pathological conditions. Notably, KRT33A is expressed during certain stages of epithelial cell differentiation, suggesting its significance in developmental biology. Its association with disease mechanisms underscores the importance of studying KRT33A not only for understanding the fundamental aspects of cell biology but also for identifying novel therapeutic targets. Recent advances in proteomics and genomics have facilitated the exploration of KRT33A's role in cancer progression and metastasis, highlighting its potential as a biomarker for prognosis and treatment response. Overall, ongoing research into KRT33A aims to unravel its functions and clinical implications, paving the way for innovative approaches in diagnosing and treating epithelial-related diseases.
