Rabbit Polyclonal MTCH1 Antibody

MTCH1 (Mitochondrial Carrier 1 Homolog), also known as LETM1-dependent mitochondrial protein, is a mitochondrial outer membrane protein implicated in diverse cellular processes, including apoptosis, metabolism, and mitochondrial architecture. It belongs to the solute carrier family (SLC) and shares structural homology with mitochondrial carrier proteins. MTCH1 interacts with pro-apoptotic proteins like BAX and BAK, facilitating their recruitment to mitochondria during apoptosis. Studies suggest its role in regulating mitochondrial metabolism, particularly in lipid metabolism and cristae organization. MTCH1 antibodies are essential tools for detecting MTCH1 expression, localization, and interactions in research. They are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to investigate MTCH1's involvement in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. Recent research highlights MTCH1's potential as a therapeutic target, as its dysregulation correlates with altered mitochondrial function and cell survival pathways. Antibodies against MTCH1 also aid in studying its tissue-specific expression patterns and post-translational modifications, contributing to a deeper understanding of mitochondrial biology and disease mechanisms.