| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein 64 homolog, isoforms 3 and 4, Zfp-64, Zinc finger protein 338, ZFP64, ZNF338 |
| Entrez GeneID | 55734 |
| WB Predicted band size | 72.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ZFP64 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 525-551 amino acids from the C-terminal region of human ZFP64. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是关于ZFP64抗体的3篇参考文献示例(内容基于公开文献概括，非真实引用，仅作格式参考)：
---
1. **文献名称**：*ZFP64 promotes leukemogenesis through MYC-mediated transcriptional reprogramming*
**作者**：Smith J, et al.
**摘要**：该研究利用ZFP64抗体进行染色质免疫沉淀(ChIP)实验，揭示了ZFP64在急性髓系白血病中通过调控MYC转录网络驱动肿瘤发生，为靶向治疗提供新思路。
2. **文献名称**：*ZFP64 modulates antiviral responses by regulating interferon-stimulated gene expression*
**作者**：Chen L, et al.
**摘要**：通过Western blot和免疫荧光(使用ZFP64抗体)，研究发现ZFP64与IRF3相互作用，负调控I型干扰素信号通路，影响宿主对病毒感染的免疫反应。
3. **文献名称**：*Epigenetic regulation of ZFP64 in colorectal cancer progression*
**作者**：Wang Y, et al.
**摘要**：研究通过免疫组化(ZFP64抗体)发现ZFP64在结直肠癌中高表达，其通过结合Wnt/β-catenin通路基因增强肿瘤侵袭性，提示其作为预后标志物的潜力。
---
如需真实文献，建议在PubMed或Google Scholar中搜索关键词“ZFP64 antibody”或“ZFP64 function”。
ZFP64 (Zinc Finger Protein 64), also known as ZNF338. is a transcription factor containing multiple C2H2-type zinc finger domains, which enable sequence-specific DNA binding. It plays roles in transcriptional regulation, immune responses, and cellular differentiation. Studies suggest ZFP64 interacts with NF-κB signaling, influencing inflammatory gene expression, and may participate in antiviral defense by regulating interferon-stimulated genes. Dysregulation of ZFP64 has been linked to cancers, including leukemia and hepatocellular carcinoma, where it can act as an oncogene or tumor suppressor depending on context.
ZFP64 antibodies are immunological tools developed to detect and study the expression, localization, and function of ZFP64 in various biological systems. These antibodies are typically validated for applications like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and chromatin immunoprecipitation (ChIP). Researchers use them to explore ZFP64's involvement in disease mechanisms, transcriptional networks, and immune regulation. Commercial ZFP64 antibodies are often raised in rabbits or mice, targeting specific epitopes within the protein's N-terminal or zinc finger regions. Proper validation, including knockout controls, is essential due to potential cross-reactivity with other zinc finger proteins. Their availability supports ongoing investigations into ZFP64's role in development, cancer, and host-pathogen interactions.
×
