Rabbit Polyclonal FSHB Antibody

The follicle-stimulating hormone beta subunit (FSHB) antibody targets the β-subunit of follicle-stimulating hormone (FSH), a glycoprotein critical for reproductive functions. FSH, produced by the anterior pituitary gland, comprises α- and β-subunits. While the α-subunit is shared with other hormones (e.g., LH, TSH), the β-subunit confers FSH-specific biological activity, including regulating gonadal development, gametogenesis, and steroidogenesis. Antibodies against FSHB are essential tools in research and diagnostics to detect, quantify, or neutralize FSH in biological samples. They help study FSH expression patterns, receptor interactions, and hormonal regulation in reproductive disorders such as infertility, polycystic ovary syndrome (PCOS), or hypogonadism. In clinical settings, FSHB antibodies are used in immunoassays to measure FSH levels, aiding in diagnosing pituitary-gonadal axis dysfunctions. Rarely, autoimmune conditions may involve anti-FSHB antibodies that interfere with FSH signaling, contributing to reproductive pathologies. Monoclonal FSHB antibodies, with high specificity, are valuable in therapeutic development, including potential fertility treatments or targeted therapies for FSH-secreting tumors. Validation of these antibodies requires careful assessment of cross-reactivity with similar subunits. Overall, FSHB antibodies bridge basic endocrine research and applied clinical diagnostics, enhancing understanding and management of reproductive health.